Evidence map›Paper›PMID 35127718›Full record

ArticleFrontiers in cell and developmental biology2021

B1 siRNA Increases

Sakawdaurn Yasom, Wilunplus Khumsri, Papatson Boonsongserm, Nakarin Kitkumthorn, Preecha Ruangvejvorachai, Apasee Sooksamran, Rujira Wanotayan, Apiwat Mutirangura

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sakawdaurn YasomCenter of Excellence in Molecular Genetics of Cancer and Human Disease, Department of Anatomy, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand.
Wilunplus KhumsriCenter of Excellence in Molecular Genetics of Cancer and Human Disease, Department of Anatomy, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand.
Papatson BoonsongsermCenter of Excellence in Molecular Genetics of Cancer and Human Disease, Department of Anatomy, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand.
Nakarin KitkumthornDepartment of Oral Biology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Preecha RuangvejvorachaiDepartment of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Apasee SooksamranDepartment of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Rujira WanotayanDepartment of Radiological Technology, Faculty of Medical Technology, Mahidol University, Nakhon Pathom, Thailand.
Apiwat MutiranguraCenter of Excellence in Molecular Genetics of Cancer and Human Disease, Department of Anatomy, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand.
Chulalongkorn University · THKing Chulalongkorn Memorial Hospital · THMahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alu (B1 in rodents) hypomethylation, commonly found in diabetes mellitus patients, increases DNA damage and, consequently, delays the healing process. Alu siRNA increases Alu methylation, reduces DNA damage, and promotes cell proliferation.

Indexed as

B1 elementB1 siRNAdiabetic ratDNA damageDNA hypomethylationDNA methylationRNA-directed DNA methylationwound healing

Identifiers

PMID35127718
PMCPMC8807477
OpenAlexW4205638465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.