Evidence map›Paper›PMID 35127710›Full record

ArticleFrontiers in cell and developmental biology2021

Bridging the Gap: The Importance of TUBA1A α-Tubulin in Forming Midline Commissures.

Georgia Buscaglia, Kyle R Northington, Jayne Aiken, Katelyn J Hoff, Emily A Bates

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. A Novel PathogenicGenes · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Culturing Primary Cortical Neurons for Live-Imaging.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  8. Article
  9. Article
  10. Novel loss of function mutation inFrontiers in cellular neuroscience · 2023
    Article
  11. Pediatric Brain Maturation and Migration Disorders.Diagnostics (Basel, Switzerland) · 2022
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Georgia BuscagliaDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Kyle R NorthingtonDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Jayne AikenDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Katelyn J HoffDepartment of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Emily A BatesDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
University of Colorado Anschutz Medical Campus · US

Funding

Predoctoral Training Program in Molecular and Cellular Biology (Supplement: Mentoring in the Research Environment)T32GM136444 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI MICHAEL A MCMURRAY, Rytis Prekeris · 2020 to 2026
$3.7M
Neuroscience Training GrantT32NS099042 · NINDS · UNIVERSITY OF COLORADO DENVER · PI Nidia Calero, GIDON S FELSEN · 2016 to 2026
$2.1M
Predoctoral Training in the Genetics of Development, Disease and RegenerationT32GM141742 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI Bruce H Appel, Jeffrey Kyle Moore · 2021 to 2026
$1.9M
Ion channel mediated control of mophogen signaling for craniofacial development in mammalsR01DE025311 · NIDCR · UNIVERSITY OF COLORADO DENVER · PI BATES, EMILY · 2018 to 2023
$1.8M
Interrogating Local Microtubule Regulation Required for Presynapse Formation and MaintenanceF32NS117672 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI AIKEN, JAYNE E · 2020 to 2022
$158k
NIDCR NIH HHS R01 DE025311NIGMS NIH HHS T32 GM136444NIGMS NIH HHS T32 GM141742NINDS NIH HHS F32 NS117672NINDS NIH HHS T32 NS099042
6 · The paper itself

Abstract

Developing neurons undergo dramatic morphological changes to appropriately migrate and extend axons to make synaptic connections. The microtubule cytoskeleton, made of α/β-tubulin dimers, drives neurite outgrowth, promotes neuronal growth cone responses, and facilitates intracellular transport of critical cargoes during neurodevelopment.

Indexed as

commissure defectsMAP1Bmicrotubule cytoskeletonTUBA1A proteintubulinopathy

Identifiers

PMID35127710
PMCPMC8807549
OpenAlexW4206027674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.