Evidence map›Paper›PMID 35127702›Full record

ArticleFrontiers in cell and developmental biology2021

Regeneration of Jaw Joint Cartilage in Adult Zebrafish.

Joanna Smeeton, Natasha Natarajan, Troy Anderson, Kuo-Chang Tseng, Peter Fabian, J Gage Crump

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Reactivation of an embryonic cardiac neural crest transcriptional profile during zebrafish heart regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Craniofacial developmental biology in the single-cell era.Development (Cambridge, England) · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Cartilage regeneration in zebrafish depends on Nrg1/ErbB signaling pathway.Frontiers in cell and developmental biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Joanna SmeetonDepartment of Rehabilitation and Regenerative Medicine, Columbia Stem Cell Initiative, Columbia University Irving Medical Center, Columbia University, New York, NY, United States.
Natasha NatarajanDepartment of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Troy AndersonDepartment of Rehabilitation and Regenerative Medicine, Columbia Stem Cell Initiative, Columbia University Irving Medical Center, Columbia University, New York, NY, United States.
Kuo-Chang TsengDepartment of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Peter FabianDepartment of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
J Gage CrumpDepartment of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
University of Southern California · USColumbia University · US

Funding

Progenitor Regulation in Craniofacial Development and RegenerationR35DE027550 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CRUMP, GAGE D · 2017 to 2024
$8.0M
Endogenous stem cells in jaw joint cartilage and ligament regenerationR00DE027218 · NIDCR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SMEETON, JOANNA MARJORIE · 2020 to 2022
$729k
Single-cell analysis of the craniofacial skeletal stem cell nicheK99DE029858 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FABIAN, PETER · 2020 to 2021
$206k
NIDCR NIH HHS K99 DE029858NIDCR NIH HHS R00 DE027218NIDCR NIH HHS R35 DE027550
6 · The paper itself

Abstract

The poor intrinsic repair capacity of mammalian joint cartilage likely contributes to the high incidence of arthritis worldwide. Adult zebrafish can regenerate many structures that show limited or no healing capacity in mammals, including the jawbone. To test whether zebrafish can also regenerate damaged joints, we developed a surgical injury model in which the zebrafish jaw joint is destabilized

Indexed as

cartilagejointosteoarthritisregenerationzebrafish

Identifiers

PMID35127702
PMCPMC8811260
OpenAlexW4206556642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.