Evidence map›Paper›PMID 35127664›Full record

ReviewFrontiers in bioengineering and biotechnology2022

Synthetic Biology-Driven Microbial Production of Resveratrol: Advances and Perspectives.

Chao Feng, Jing Chen, Wenxin Ye, Kaisen Liao, Zhanshi Wang, Xiaofei Song, Mingqiang Qiao

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Resveratrol-EnrichedNutrients · 2026
    Article
  3. Review
  4. Review
  5. Phytochemical Composition ofAdvances in pharmacological and pharmaceutical sciences · 2025
    Review
  6. Denovo Production of Resveratrol by Engineered Rice Wine StrainJournal of fungi (Basel, Switzerland) · 2024
    Article
  7. Overexpression ofHeliyon · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chao FengDepartment of Urology, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Jing ChenDepartment of Urology, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Wenxin YeDepartment of Urology, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Kaisen LiaoDepartment of Urology, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Zhanshi WangDepartment of Urology, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Xiaofei SongThe Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin, China.
Mingqiang QiaoThe Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resveratrol, a bioactive natural product found in many plants, is a secondary metabolite and has attracted much attention in the medicine and health care products fields due to its remarkable biological activities including anti-cancer, anti-oxidation, anti-aging, anti-inflammation, neuroprotection and anti-glycation. However, traditional chemical synthesis and plant extraction methods are impractical for industrial resveratrol production because of low yield, toxic chemical solvents and environmental pollution during the production process. Recently, the biosynthesis of resveratrol by constructing microbial cell factories has attracted much attention, because it provides a safe and efficient route for the resveratrol production. This review discusses the physiological functions and market applications of resveratrol. In addition, recent significant biotechnology advances in resveratrol biosynthesis are systematically summarized. Furthermore, we discuss the current challenges and future prospects for strain development for large-scale resveratrol production at an industrial level.

Indexed as

metabolic engineeringmicroorganismphysiological functionresveratrolsynthetic biology

Identifiers

PMID35127664
PMCPMC8811299

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.