ReviewFrontiers in public health2021
Barker Hypothesis and Hypertension.
Review in Frontiers in public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06773299 (ENhancing Intergenerational HeAlth in Nigeria), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ENhancing Intergenerational HeAlth in Nigeria: Peripartum as Critical Life StagE for CardioVascular Health
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Association of a Vegan Diet during Pregnancy with Maternal and Child Outcomes: A Systematic Review.Nutrients · 2024Pooled it
- Neonatal Acute Kidney Injury-An Australian and New Zealand Perspective.Journal of paediatrics and child health · 2026Review
- Preterm birth and birth weight extremes are associated with periodontal disease and tooth loss in the ARIC study.Scientific reports · 2026Article
- Decoding type 5 diabetes using spatial omics: microarchitectural and molecular mechanisms of malnutrition-associated diabetes.Frontiers in endocrinology · 2026Review
- Long-term health in individuals born preterm or with low birth weight: A cohort study.Pediatric research · 2025Article
- Ambient Air Pollution and Congenital Heart Disease: Updated Evidence and Future Challenges.Antioxidants (Basel, Switzerland) · 2025Review
- The Significance of Plant Nutrition in the Creation of the Intestinal Microbiota-Prevention of Chronic Diseases: A Narrative Review.Medicina (Kaunas, Lithuania) · 2024Review
- The association of birth weight and current BMI on the risk of hypertension: the Tohoku medical megabank community-based cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Morphometric analysis of the intergenerational effects of protein restriction on nephron endowment in mice.Heliyon · 2024Article
- Early metabolic and hemodynamic indicators of kidney dysfunction in mice offspring from parental low protein diet.Molecular and cellular pediatrics · 2024Article
- [The association between preterm birth and hypertension].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Review
- Inflammation: Is It a Healer, Confounder, or a Promoter of Cardiometabolic Risks?Biomolecules · 2024Review
- Acute Kidney Injury in Neonatal Intensive Care Unit: Epidemiology, Diagnosis and Risk Factors.Journal of clinical medicine · 2024Review
- T-cells regulate albuminuria but not hypertension, renal histology, or the medullary transcriptome in the Dahl SSCD247American journal of physiology. Renal physiology · 2024Article
- Prematurity and Low Birth Weight and Their Impact on Childhood Growth Patterns and the Risk of Long-Term Cardiovascular Sequelae.Children (Basel, Switzerland) · 2023Review
- Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective.Frontiers in neuroscience · 2023Review
- Article
- Type 5 Diabetes- The Rejuvenated Spirit from a Ghost of the Past.Indian journal of endocrinology and metabolismArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early onset hypertension is one of many major medical disorders that have evolved over the current millennium across both the developing as well as the developed world. Though various mechanisms have been postulated for the evolution of hypertension in these individuals, one of the most relevant ones is that of low birth weight and its association with hypertension. Barker from historical evidence has postulated the foetal onset adult disease (FOAD) or Thrifty phenotype on Low Birth Weight (LBW) associated hypertension. Later, Brenner highlighted the importance of low nephron mass and future implications. In this review we elaborate the mechanisms that were postulated for LBW-related hypertension as well the potential antihypertensive therapy that may be used in these individuals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.