Evidence map›Paper›PMID 35127562›Full record

ArticleFrontiers in cellular and infection microbiology2021

Activity of Sulbactam-Durlobactam and Comparators Against a National Collection of Carbapenem-Resistant

Dimitra Petropoulou, Maria Siopi, Sophia Vourli, Spyros Pournaras

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Resistance ofPathogens (Basel, Switzerland) · 2025
    Pooled it
  2. Characterization ofAntimicrobial agents and chemotherapy · 2024
    Trial
  3. ConsistentAntimicrobial agents and chemotherapy · 2026
    Article
  4. Indian Society of Critical Care Medicine Guidelines on Evidence-based Recommendations for the Treatment of Carbapenem-resistant Enterobacterales, Carbapenem-resistantIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Turning the Tide Against Carbapenem-resistantOpen forum infectious diseases · 2025
    Article
  10. Genomic characterization of Carbapenem-Resistant Acinetobacter baumannii clinical strains resistant to Sulbactam/Durlobactam from Italy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  11. Article
  12. Review
  13. Sulbactam-Durlobactam: A Novel Antibiotic Combination for the Treatment ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Review
  14. The challenges of difficult-to-treatClinical microbiology reviews · 2024
    Review
  15. Unveiling the Secrets ofInternational journal of molecular sciences · 2024
    Review
  16. Antibiotic Treatment of Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2024
    Review
  17. Treatment Strategies of Colistin ResistanceAntibiotics (Basel, Switzerland) · 2024
    Review
  18. Article
  19. Microbiology spectrum · 2024
    Article
  20. Antimicrobial agents and chemotherapy · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dimitra PetropoulouLaboratory of Clinical Microbiology, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Maria SiopiLaboratory of Clinical Microbiology, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Sophia VourliLaboratory of Clinical Microbiology, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Spyros PournarasLaboratory of Clinical Microbiology, Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
National and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

objectivesThe aim of this study is to evaluate the

methodsOne hundred ninety CRAB isolates were collected from clinical samples of patients hospitalized in 11 hospitals throughout Greece during 2015.

resultsDurlobactam restored sulbactam activity against the majority of the strains tested, with SD exhibiting the lowest MIC

conclusionsThis study demonstrated the potential utility of SD for the treatment of infections caused by

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsAzabicyclo CompoundsCarbapenemsColistinDrug CombinationsGreeceHumansMicrobial Sensitivity TestsSulbactamAnti-Bacterial AgentsAzabicyclo CompoundsCarbapenemsColistinDrug CombinationsSulbactamsulbactam-durlobactambeta-lactamase inhibitorcarbapenemasesCRAB infectionsdiazabicyclooctanedurlobactamhospital infectionsserine-type beta-lactamasessulbactam-durlobactam-imipenem

Identifiers

PMID35127562
PMCPMC8812809
OpenAlexW4206075785

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.