Evidence map›Paper›PMID 35127456›Full record

ArticleToxicology reports2022

Development of a thermal spray coating aerosol generator and inhalation exposure system.

Aliakbar A Afshari, Walter McKinney, Jared L Cumpston, Howard D Leonard, James B Cumpston, Terence G Meighan, Mark Jackson, Sherri Friend, Vamsi Kodali, Eun Gyung Lee and 1 more

Abstract read
In one paragraph

Article in Toxicology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aliakbar A AfshariHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, 26508, United States.
Walter McKinneyHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, 26508, United States.
Jared L CumpstonHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, 26508, United States.
Howard D LeonardHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, 26508, United States.
James B CumpstonHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, 26508, United States.
Terence G MeighanHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, 26508, United States.
Mark JacksonHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, 26508, United States.
Sherri FriendHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, 26508, United States.
Vamsi KodaliHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, 26508, United States.
Eun Gyung LeeRespiratory Health Division, National Institute for Occupational Safety and Health, Morgantown, WV, 26508, United States.
James M AntoniniHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, 26508, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thermal spray coating involves spraying a product (oftentimes metal) that is melted by extremely high temperatures and then applied under pressure onto a surface. Large amounts of a complex metal aerosol (e.g., Fe, Cr, Ni, Zn) are formed during the process, presenting a potentially serious risk to the operator. Information about the health effects associated with exposure to these aerosols is lacking. Even less is known about the chemical and physical properties of these aerosols. The goal was to develop and test an automated thermal spray coating aerosol generator and inhalation exposure system that would simulate workplace exposures. An electric arc wire-thermal spray coating aerosol generator and exposure system was designed and separated into two areas: (1) an enclosed room where the spray coating occurs; (2) an exposure chamber with different measurement devices and controllers. The physicochemical properties of aerosols generated during electric arc wire-thermal spray coating using five different consumable wires were examined. The metal composition of each was determined by inductively coupled plasma-atomic emission spectroscopy (ICP-AES), including two stainless-steel wires [PMET720 (82 % Fe, 13 % Cr); PMET731(66 % Fe, 26 % Cr)], two Ni-based wires [PMET876 (55 % Ni, 17 % Cr); PMET885 (97 % Ni)], and one Zn-based wire [PMET540 (99 % Zn)]. The particles generated regardless of composition were poorly soluble, complex metal oxides and mostly arranged as chain-like agglomerates and similar in size distribution as determined by micro-orifice uniform deposit impactor (MOUDI) and electrical low-pressure impactor (ELPI). To allow for continuous, sequential spray coating during a 4-hr exposure period, a motor rotated the metal pipe to be coated in a circular and up-and-down direction. In a pilot animal study, male Sprague-Dawley rats were exposed to aerosols (25 mg/m

Indexed as

Inhalation systemMetalsParticle sizeParticulatesThermal spray coating

Identifiers

PMID35127456
PMCPMC8810300

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.