Evidence map›Paper›PMID 35127177›Full record

ArticleAIDS research and treatment2022

Incidence of Mortality among Under-Five-Year-Old Children Born to Women Living with HIV and Those Born to Women Not Living with HIV in Botswana: A 5-Year Retrospective Study.

Onalethata Lesetedi, Jose Gaby Tshikuka, Shimeles G Hamda, Mgaywa Gilbert Mjungu Damas Magafu, Roy Tapera, Tiny Masupe, Julius Chacha Mwita

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Article in AIDS research and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Development and implementation of a modified IMEGH Paediatric Advanced Life Support course in a low-resource setting.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2026
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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Onalethata LesetediDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Jose Gaby TshikukaDepartment of Nursing Science, Faculty of Health Sciences, National Pedagogical University, Kinshasa I, Democratic Republic of the Congo.ORCID https://orcid.org/0000-0002-7003-0614
Shimeles G HamdaDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Mgaywa Gilbert Mjungu Damas MagafuMalaria Vaccine Implementation Program (MVIP), OMS/WHO Regional Office for Africa, Cite du Djoue, Boite Postale 06, Brazzaville, Congo.
Roy TaperaSchool of Public Health, Faculty of Health Sciences, University of Botswana, Private Bag 0022, Gaborone, Botswana.
Tiny MasupeDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Julius Chacha MwitaDepartment of Internal Medicine, Faculty of Medicine, University of Botswana, Gaborone, Botswana.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundChild mortality is a core indicator for child health and wellness. Botswana reported an under-five-year-old children (UFC) mortality rate of 48 deaths per 1000 live births in 2017 against 152 deaths per 1000 live births in 1971. This was a commendable accomplishment. However, given the current country situation whereby 23% of children are born to women living with HIV, the incidence of mortality among UFC born to women living with and not living with HIV and their survival are better health metrics to inform decision making. Nevertheless, such data are still very scarce in Botswana. The study's objective was to estimate the incidence of UFC mortality among children born to women living with and not living with HIV and to compare UFC survival between the two groups.

methodsA retrospective cohort study of mortality among UFC was conducted in Botswana, including all UFC born between January 2014 and June 2018. Data were extracted from the National Under-Five Mortality Audit Committee (NUFMAC) database using a standardized data collection tool. The incidence rate of UFC death was estimated as a function of the duration from birth to death. Survival functions of UFC born to women living with and not living with HIV were plotted and compared using Kaplan-Meier survival analysis.

resultsThe overall incidence of UFC death was 4.63/1000 child months (CM) (95% CI 4.36-4.90). The incidence of UFC death among children born to women living with HIV was 6.96/1000 CM (95% CI 6.47-7.45) and that of UFC born to women not living with HIV was 4.34/1000 CM (95% CI 4.03-4.65). The overall average and standard error (SE) time to event/death for UFC born to women living with and not living with HIV was 54.80 (0.18) months. The mean (SE) time to death for UFC born to women living with HIV was 52.79 (0.41) months and that of UFC born to women not living with HIV was 55.44 (0.19) months (log-rank

conclusionDespite the commendable efforts made in reducing UFC death, the incidence of UFC death among UFC born to women living with HIV in Botswana is still higher, and their survival is shorter compared to UFC born to women not living with HIV. Child survival interventions should prioritize UFC born to women living with HIV to improve their survival.

Identifiers

PMID35127177
PMCPMC8816585

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