ArticleAnnals of medicine and surgery (2012)2022
Association of soluble receptor for advanced glycation end-products (sRAGE) serum on COVID-19 severity: A cross-sectional study.
Article in Annals of medicine and surgery (2012), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The trial behind it
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Who cites it
14 citing papers in PubMed, 17 citations in OpenAlex.
- Biomarkers and early-onset acute kidney injury in critically ill COVID-19 patients, a prospective monocentric observational study.BMC nephrology · 2025Observational
- Advanced Glycation End Products in Disease Development and Potential Interventions.Antioxidants (Basel, Switzerland) · 2025Review
- The Evaluation of New-Generation Biomarker sCD14ST Provides New Insight into COVID-19's Effect on Bone Remodeling.Journal of clinical medicine · 2025Article
- Oxidative stress and COVID-19-associated neuronal dysfunction: mechanisms and therapeutic implications.Acta biochimica et biophysica Sinica · 2023Review
- Levels of SARS-COV-2 anti-spike protein receptor-binding domain (S-RBD) IgG in Indonesian-vaccinated healthcare workers: experimental research.Annals of medicine and surgery (2012) · 2023Article
- Immunomodulation Effect of Convalescent Plasma Therapy in Severe - Critical COVID-19 Patients.Open access emergency medicine : OAEM · 2023Article
- Antiviral use in liver function abnormalities and Covid-19 patients: Serial cases.Annals of medicine and surgery (2012) · 2022Article
- Review
- Interleukin-6 (IL-6) expression of lung tissue in COVID-19 patient severity through core biopsy post mortem.Annals of medicine and surgery (2012) · 2022Article
- Glycation-Driven Inflammation: COVID-19 Severity in Pregnant Women and Perinatal Outcomes.Nutrients · 2022Article
- Advanced Glycation End Products in Health and Disease.Microorganisms · 2022Review
- Effect of combined locomotor training and aerobic exercise on increasing handgrip strength in elderly with locomotive syndrome: A randomised controlled trial.Annals of medicine and surgery (2012) · 2022Article
- National early warning score (NEWS) 2 predicts hospital mortality from COVID-19 patients.Annals of medicine and surgery (2012) · 2022Article
- Interleukin-1β and Interleukin-10 Profiles and Ratio in Serum of COVID-19 Patients and Correlation with COVID-19 Severity: A Time Series Study.International journal of general medicine · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCoronavirus disease 2019 (COVID-19) is a new health problem discovered in 2019 thus requires biomarkers that can detect early tissue damage. Soluble receptor for advanced glycation end-products (sRAGE) is a biomarker that can be used to identify early lung damage.
objectiveAnalyzing the association of serum sRAGE on COVID-19 severity.
methodsThis study employed a cross-sectional design with a consecutive sampling method. It was conducted from May 2020-October 2021. The number of participants in this study was 145 participants which were divided into 2 groups (non-severe = 47 and severe = 98). Association of sRAGE serum on COVID-19 severity was analyzed using the chi-square test, Fisher's exact test, independence
resultsThe results of blood analysis showed several blood components such as leukocytes (9896.51 ± 4949.64/μL;
conclusionThere is a significant association between serum sRAGE and COVID-19 severity and there is also a significant difference in serum sRAGE in the two groups.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.