Evidence map›Paper›PMID 35126871›Full record

ReviewWorld journal of cardiology2022

Fondaparinux: A cornerstone drug in acute coronary syndromes.

Mohammed Yunus Khan, Chandrashekhar K Ponde, Viveka Kumar, Kumar Gaurav

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mohammed Yunus KhanMedical Affairs, Dr. Reddy's Laboratories Ltd, Hyderabad 500018, India. doctorkhan26@gmail.com.
Chandrashekhar K PondeDepartment of Cardiology, P.D. Hinduja Hospital & Medical Research Centre, Mumbai 400016, India.
Viveka KumarDepartment of Cardiology, Max Super Speciality Hospital, New Delhi 110017, India.
Kumar GauravMedical Affairs, Dr. Reddy's Laboratories Ltd, Hyderabad 500018, India.
Dr. Reddy's Laboratories (India) · INMax Super Speciality Hospital · INP. D. Hinduja Hospital and Medical Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In acute coronary syndrome (ACS), the use of anticoagulants in conjunction with antiplatelet agents in the acute phase has resulted in reduced ischemic events and is more effective than either class of drug used alone. Though parenteral anticoagulation is essential at the time of diagnosis, a balance must be made between ischemic benefit and the increased risk of bleeding when prescribing anticoagulants. Adverse events associated with anticoagulants, such as heparin-induced thrombocytopenia, bleeding problems, and the need for close monitoring of anticoagulant activity, have contributed to finding agents that reduce these limitations. Studies like the Organization to Assess Strategies in Ischemic Syndromes 5 and 6 and their meta-analysis have proven the efficacy of Fondaparinux over the entire ACS spectrum. The convenience of administration (once daily), lack of monitoring, reduction in mortality, and better safety profile make Fondaparinux a simple and effective anti-coagulant for the management of ACS.

Indexed as

Acute coronary syndromeAnti-coagulant therapyAntiplatelet therapyEnoxaparinFondaparinuxUnfractionated heparin

Identifiers

PMID35126871
PMCPMC8788176
OpenAlexW4206175805

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.