ArticleWorld journal of gastrointestinal surgery2022
Association of anastomotic leakage with long-term oncologic outcomes of patients with esophagogastric junction cancer.
Article in World journal of gastrointestinal surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 2 citations in OpenAlex.
- Transitioning from hand-sewn to circular stapled cervical anastomosis after minimally invasive esophagectomy: a Western centre propensity score matching analysis.Updates in surgery · 2026Article
- Outcomes of transmediastinal esophagectomy for patients with esophagogastric junction cancers.International journal of clinical oncology · 2026Article
- Complications and survival after Ivor Lewis esophagectomy.BMC cancer · 2026Article
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Authors and funding
11 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite improvements in surgical procedures and peri-operative patients management, the postoperative complications in esophagogastric junction (EGJ) cancer remain high because of technical aspects. Several studies have indicated the negative influence of postoperative infectious complications on long-term survival after gastrointestinal surgery. However, no study has shown the association between postoperative complications and long-term survival of patients with EGJ cancer.
aimTo elucidate influence of postoperative complications on the long-term outcomes of patients with EGJ cancer.
methodsA total of 122 patients who underwent surgery for EGJ cancer at the Keio University were included in this study. We examined the association between complications and long-term oncologic outcomes.
resultsIn all patients, the 3-year overall survival (OS) rate was 71.9%, and the recurrence-free survival (RFS) rate was 67.5%. Compared with patients without anastomotic leakage, those with anastomotic leakage had poor median OS (8 mo
conclusionAnastomotic leakage was significantly associated with long-term oncologic outcomes of patients with EGJ cancer, especially those who underwent intrathoracic anastomosis. Cervical anastomosis with subtotal esophagectomy may be an option for the patients who are at high risk for anastomotic leakage.
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