Evidence map›Paper›PMID 35126752›Full record

ArticleJournal of medicine and life

Morphohistochemical alterations of neurons of the supraoptic nucleus of the rat hypothalamus at different durations of the photoperiod and melatonin administration.

Roman Yevgenovych Bulyk, Oleksiy Vasyliovych Smetanyuk, Kateryna Vasylivna Vlasova, Mariana Ivanivna Kryvchanska, Vladyslav Romanovych Yosypenko, Volodymyr Leonidovych Voloshyn, Kateryna Yuriivna Tymchuk, Tetyana Sergiivna Bulyk, Larysa Vasylivna Rynzhuk, Michael Ivanovych Sheremet and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Roman Yevgenovych BulykDepartment of Medical Biology and Genetics, Bukovinian State Medical University, Chernivtsi, Ukraine.
Oleksiy Vasyliovych SmetanyukDepartment of Medical Biology and Genetics, Bukovinian State Medical University, Chernivtsi, Ukraine.
Kateryna Vasylivna VlasovaDepartment of Medical Biology and Genetics, Bukovinian State Medical University, Chernivtsi, Ukraine.
Mariana Ivanivna KryvchanskaDepartment of Medical Biology and Genetics, Bukovinian State Medical University, Chernivtsi, Ukraine.
Vladyslav Romanovych YosypenkoDepartment of Medical Biology and Genetics, Bukovinian State Medical University, Chernivtsi, Ukraine.
Volodymyr Leonidovych VoloshynDepartment of Medical Biology and Genetics, Bukovinian State Medical University, Chernivtsi, Ukraine.
Kateryna Yuriivna TymchukDepartment of Medical Biology and Genetics, Bukovinian State Medical University, Chernivtsi, Ukraine.
Tetyana Sergiivna BulykDepartment of Obstetrics and Gynecology, Bukovinian State Medical University, Chernivtsi, Ukraine.
Larysa Vasylivna RynzhukDepartment of Obstetrics and Gynecology, Bukovinian State Medical University, Chernivtsi, Ukraine.
Michael Ivanovych SheremetSurgery Department No.1, Bukovinian State Medical University, Chernivtsi, Ukraine.
Dmytro Volodymyrovych ProniaievDepartment of Anatomy, Clinical Anatomy and Operative Surgery, Bukovinian State Medical University, Chernivtsi, Ukraine.
Bukovinian State Medical University · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the morphologic and histochemical organization of neurons of the hypothalamic supraoptic nucleus in rats exposed to different durations of photoperiod and injection of melatonin. Morphometric and histochemical analyses of neurons were performed after staining brain histological sections for RNA. Prolonged illumination leads to more pronounced changes in the parameters of hypothalamic structures at 2 a.m. than at 2 p.m., particularly decreasing the concentration of RNA in the cell nuclei. The use of exogenous melatonin does not normalize the revealed changes in the parameters of the studied structures of the neurons of the supraoptic nucleus of the hypothalamus caused by the prolonged stay of rats under conditions of constant illumination.

Indexed as

MelatoninSupraoptic NucleusAnimalsHypothalamusNeuronsParaventricular Hypothalamic NucleusPhotoperiodRatsMelatoninhypothalamusmelatoninphotoperiodsupraoptic nucleus

Identifiers

PMID35126752
PMCPMC8811669
OpenAlexW4210861424

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.