Evidence map›Paper›PMID 35126748›Full record

ArticleJournal of medicine and life

Association of AGTR1 (rs5186), VDR (rs2228570) genes polymorphism with blood pressure elevation in patients with essential arterial hypertension.

Marianna Mykolaivna Semianiv, Larysa Petrivna Sydorchuk, Valentyna Stepanivna Dzhuryak, Oleg Vasylovich Gerush, Oleg Vasylovich Gerush, Alina Oleksandrivna Palamar, Natalia Yaroslavivna Muzyka, Oksana Mykolaivna Korovenkova, Olesia Mykhaylivna Blazhiievska, Valeriia Valeriivna Sydor and 3 more

Abstract read
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In one paragraph

Article in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marianna Mykolaivna SemianivFamily Medicine Department, Bukovinian State Medical University, Chernivtsi, Ukraine.
Larysa Petrivna SydorchukFamily Medicine Department, Bukovinian State Medical University, Chernivtsi, Ukraine.
Valentyna Stepanivna DzhuryakPharmacy Department, Bukovinian State Medical University, Chernivtsi, Ukraine.
Oleg Vasylovich GerushPharmacy Department, Bukovinian State Medical University, Chernivtsi, Ukraine.
Oleg Vasylovich GerushPharmacy Department, Bukovinian State Medical University, Chernivtsi, Ukraine.
Alina Oleksandrivna PalamarPharmacy Department, Bukovinian State Medical University, Chernivtsi, Ukraine.
Natalia Yaroslavivna MuzykaPharmacy Department, Bukovinian State Medical University, Chernivtsi, Ukraine.
Oksana Mykolaivna KorovenkovaPharmacy Department, Bukovinian State Medical University, Chernivtsi, Ukraine.
Olesia Mykhaylivna BlazhiievskaPharmacy Department, Bukovinian State Medical University, Chernivtsi, Ukraine.
Valeriia Valeriivna SydorPharmacy Department, Bukovinian State Medical University, Chernivtsi, Ukraine.
Andrii Ruslanovich SydorchukEmergency and Trauma Surgery Department, St. Anna Hospital, Herne, Germany.
Igor Oleksandrovich SemianivPhthisiology and Pulmonology Department, Bukovinian State Medical University, Chernivtsi, Ukraine.
Ruslan Igorovich SydorchukGeneral Surgery Department, Bukovinian State Medical University, Chernivtsi, Ukraine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential arterial hypertension (EAH) is a polygenic disease due to environmental, genetic, and epigenomic factors. The study aimed to establish the association of single nucleotide polymorphism (SNP) of AGTR1 (rs5186) and VDR (rs2228570) genes with the blood pressure (BP) elevation in EAH patients. 100 EAH subjects with hypertensive-mediated organ damaging (2

Indexed as

HypertensionReceptor, Angiotensin, Type 1AgedBlood PressureCase-Control StudiesFemaleGenetic Predisposition to DiseaseGenotypeHumansMaleMiddle AgedPolymorphism, Single NucleotideReceptors, CalcitriolAGTR1 protein, humanReceptor, Angiotensin, Type 1Receptors, CalcitriolVDR protein, humanAGTR1 – Angiotensin II receptor type 1AGTR1 (rs5186)BMI – Body mass indexBP – Blood pressureCVD – Cardiovascular diseasesDBP – Diastolic blood pressureEAH – Essential arterial hypertensionessential arterial hypertensiongene polymorphismRAAS – Renin-angiotensin-aldosterone systemSBP – Systolic blood pressureVDR (rs2228570)VDR – Vitamin D receptorWC – Waist circumferenceWHR – Waist-to-hip ratio

Identifiers

PMID35126748
PMCPMC8811662

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.