Evidence map›Paper›PMID 35126538›Full record

ArticleIranian journal of veterinary research2021

A neuroanatomical study of the feline brain using MRI and mulligan staining: functional and pathological considerations.

E Díaz Martínez, M D Ayala Florenciano, A Arencibia Espinosa, M Soler Laguía, D Kilroy, F Martínez Gomariz, G Ramírez Zarzosa

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Article in Iranian journal of veterinary research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

E Díaz MartínezDepartment of Anatomy and Compared Pathological Anatomy, Veterinary Faculty, Campus de Espinardo, University of Murcia, 30100, Murcia, Spain.
M D Ayala FlorencianoDepartment of Anatomy and Compared Pathological Anatomy, Veterinary Faculty, Campus de Espinardo, University of Murcia, 30100, Murcia, Spain.
A Arencibia EspinosaDepartment of Morphology, Veterinary Faculty, University of Las Palmas de Gran Canaria, Trasmontaña, Arucas, 35413, Las Palmas, Spain.
M Soler LaguíaDepartment of Medicine and Surgery, Veterinary Faculty, Campus de Espinardo, University of Murcia, 30100, Murcia, Spain.
D KilroyDivision of Veterinary Science Centre, University College Dublin, School of Veterinary Medicine, University of Dublin, Belfield, Dublin 4, Ireland.
F Martínez GomarizDepartment of Anatomy and Compared Pathological Anatomy, Veterinary Faculty, Campus de Espinardo, University of Murcia, 30100, Murcia, Spain.
G Ramírez ZarzosaDepartment of Anatomy and Compared Pathological Anatomy, Veterinary Faculty, Campus de Espinardo, University of Murcia, 30100, Murcia, Spain.
Universidad de Murcia · ESUniversidad de Las Palmas de Gran Canaria · ESUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite multiple studies describing accurate diagnoses using advanced neuroimaging techniques, low and mid-field magnetic resonance imaging (MRI) are still the most frequent scanners in veterinary clinics. To date, these studies in cats do not show a clear distinction of nerve centres in MRI data.

aimsThe objective of this study is to determine the efficacy of Mulligan histological staining as a tool in facilitating the location and identification of the main structures of the feline brain in MRI. This study aims to facilitate the interpretation of MRI obtained with these types of scanners.

methodsA total of 10 feline brains were used. One specimen was used for MRI (T2 sequence using a 1.5T scanner). The other 9 brains were sectioned and stained with the three Mulligan staining techniques (Mulligan, Le Masurier and Robert).

resultsThe uptake of stain by the grey matter in these sections allowed the determination of the location and the limits of these nervous structures within the brain. The histological location of these structures was correlated with the MRI scans, leading to the successful identification of many small, indistinct nuclei.

conclusionMulligan staining is proposed as a tool that facilitates the location of nerve structures in comparison with data from the most frequently-used MRI scanners in veterinary clinics.

Indexed as

FelineMRIMulligan stainingNervous nucleiNeuroanatomy

Identifiers

PMID35126538
PMCPMC8806173
OpenAlexW4210848166

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.