Evidence map›Paper›PMID 35126389›Full record

ArticleFrontiers in immunology2022

An Artifact in Intracellular Cytokine Staining for Studying T Cell Responses and Its Alleviation.

Zheng Gong, Qing Li, Jiayuan Shi, Guangwen Ren

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zheng GongThe Jackson Laboratory, Bar Harbor, ME, United States.
Qing LiThe Jackson Laboratory, Bar Harbor, ME, United States.
Jiayuan ShiThe Jackson Laboratory, Bar Harbor, ME, United States.
Guangwen RenThe Jackson Laboratory, Bar Harbor, ME, United States.
Jackson Laboratory · USThe JAX Cancer Center

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI William Carl Skarnes · 1985 to 2026
$61.9M
Lung Resident Mesenchymal Cells in the Pre-Metastatic Niche FormationR01CA251433 · NCI · JACKSON LABORATORY · PI Guangwen Ren · 2021 to 2026
$2.9M
The Role of Lung Resident Mesenchymal Stem Cells in Post-Chemotherapy Lung Metastases of Breast CancerR37CA237307 · NCI · JACKSON LABORATORY · PI Guangwen Ren · 2020 to 2026
$2.8M
Mesenchymal Stromal Cells and Stromal Fibroblasts in Radiotherapy ResistanceR00CA188093 · NCI · JACKSON LABORATORY · PI REN, GUANGWEN · 2017 to 2019
$722k
NCI NIH HHS P30 CA034196NCI NIH HHS R00 CA188093NCI NIH HHS R01 CA251433NCI NIH HHS R37 CA237307
6 · The paper itself

Abstract

Intracellular cytokine staining (ICS) is a widely employed

Indexed as

BiomarkersLymphocyte ActivationAnimalsArtifactsBreast NeoplasmsCell LineCytokinesDisease Models, AnimalFemaleFlow CytometryHumansHydrogen PeroxideIntracellular SpaceLeukocyte CountMiceMice, KnockoutBiomarkersCytokinesHydrogen Peroxidecancerhydrogen peroxideimmunosuppressioninflammationintracellular cytokine stainingneutrophils

Identifiers

PMID35126389
PMCPMC8813780
OpenAlexW4205796896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.