Evidence map›Paper›PMID 35126376›Full record

ArticleFrontiers in immunology2021

Association Between Autoimmune Diseases and Spontaneous Cervicocranial Arterial Dissection.

Hao Li, Pu Song, Wei Yang, Le Yang, Shanshan Diao, Shicun Huang, Yiqing Wang, Xingshun Xu, Yi Yang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hao LiDepartments of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Pu SongDepartments of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Wei YangDepartments of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Le YangSchool of Public Health, Fujian Medical University, Fuzhou, China.
Shanshan DiaoDepartments of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Shicun HuangDepartments of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yiqing WangDepartments of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Xingshun XuDepartments of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yi YangDepartments of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Soochow University · CNFirst Affiliated Hospital of Soochow University · CNFujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of biopsies and reports showed autoimmune diseases might be involved in the process of local inflammation related to spontaneous cervicocranial arterial dissection (SCCAD) occurrence. This retrospective case-control study examined the association between SCCADs and autoimmune diseases in patients and control subjects from 2014 to 2020. SCCAD patients and age/sex-matched control subjects were recruited, and clinical data were collected. SCCAD was confirmed by digital subtraction angiography or high-resolution magnetic resonance imaging. The study included 215 SCCAD patients and 430 control subjects. Totally, 135 (62.8%) of the 215 cases were found SCCAD in the anterior circulation, 26 (12.0%) patients involved multiple vessels. Autoimmune disease occurred in 27 (12.6%) cases with SCCAD and 4 (0.9%) control subjects (p<0.001). A conditional multivariable logistic regression model was used to calculate the odds ratio for SCCAD among patients with a history of autoimmune disease, adjusting for hypertension, diabetes, hyperlipidemia, and smoking. After adjustment, autoimmune diseases were associated with SCCAD (p<0.001). After sub-analysis by a similar modeling strategy, significant associations were still observed in different subgroups, such as female group and male group as well as intramural hematoma (IMH) group and Non-IHM group. The association of SCCAD with autoimmune disease suggested that autoimmune mechanisms may be involved in some etiologies of SCCAD.

Indexed as

Disease SusceptibilityAdultAgedAortic DissectionAutoimmune DiseasesAutoimmunityBiomarkersCase-Control StudiesComorbidityFemaleGiant Cell ArteritisHumansMaleMiddle AgedOdds RatioBiomarkersautoimmunecervicocranial arterial dissectioninflammatoryinflammatory autoimmune diseaseneurological disease

Identifiers

PMID35126376
PMCPMC8814437
OpenAlexW4206928473

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.