Evidence map›Paper›PMID 35126371›Full record

ReviewFrontiers in immunology2021

Role of Lipid Rafts in Pathogen-Host Interaction - A Mini Review.

Rakesh Kulkarni, Erik A C Wiemer, Wen Chang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 68 citations in OpenAlex.

  1. Ergosterol from Yeasts PromotesInternational journal of molecular sciences · 2026
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  15. Extracellular vesicles decoying across host immunity.Journal of leukocyte biology · 2025
    Review
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Rakesh KulkarniMolecular and Cell Biology, Taiwan International Graduate Program, National Defense Medical Center, Academia Sinica and Graduate Institute of Life Science, Taipei, Taiwan.
Erik A C WiemerMedical Oncology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, Netherlands.
Wen ChangInstitute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Academia Sinica · TWErasmus MC Cancer Institute · NLInstitute of Molecular Biology, Academia Sinica · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid rafts, also known as microdomains, are important components of cell membranes and are enriched in cholesterol, glycophospholipids and receptors. They are involved in various essential cellular processes, including endocytosis, exocytosis and cellular signaling. Receptors are concentrated at lipid rafts, through which cellular signaling can be transmitted. Pathogens exploit these signaling mechanisms to enter cells, proliferate and egress. However, lipid rafts also play an important role in initiating antimicrobial responses by sensing pathogens

Indexed as

Disease SusceptibilityHost-Pathogen InteractionsAnimalsApoptosisCytokinesEndocytosisGene Expression RegulationHumansImmunomodulationMajor Vault ProteinMembrane MicrodomainsOxidation-ReductionProtein BindingReceptors, Pattern RecognitionSignal TransductionVault Ribonucleoprotein ParticlesCytokinesMajor Vault ProteinReceptors, Pattern RecognitionVault Ribonucleoprotein Particlescell entrylipid raftsmajor vault proteinpathogen-host interactionsvaccinia virus

Identifiers

PMID35126371
PMCPMC8810822
OpenAlexW4206631575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.