Evidence map›Paper›PMID 35126352›Full record

ArticleFrontiers in immunology2021

Silica Induction of Diverse Inflammatory Proteome in Lungs of Lupus-Prone Mice Quelled by Dietary Docosahexaenoic Acid Supplementation.

Lichchavi D Rajasinghe, Melissa A Bates, Abby D Benninghoff, Kathryn A Wierenga, Jack R Harkema, James J Pestka

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lichchavi D RajasingheDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States.
Melissa A BatesDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States.
Abby D BenninghoffDepartment of Animal, Dairy and Veterinary Sciences, School of Veterinary Medicine, Utah State University, Logan, UT, United States.
Kathryn A WierengaDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, United States.
Jack R HarkemaDepartment of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MI, United States.
James J PestkaDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States.
Michigan State University · USUtah State University · US

Funding

MULTIDISCIPLINARY TRAINING IN ENVIRONMENTAL TOXICOLOGYT32ES007255 · NIEHS · MICHIGAN STATE UNIVERSITY · PI JOHN J LAPRES · 1989 to 2026
$9.3M
Role of alveolar macrophage in omega-3 fatty acid amelioration of silica-triggered autoimmunity.R01ES027353 · NIEHS · MICHIGAN STATE UNIVERSITY · PI Andrew Olive · 2017 to 2026
$4.8M
Omega-3 Fatty Acid Suppression of Silica-induced Inflammasome Activation in a Novel Alveolar Macrophage ModelF31ES030593 · NIEHS · MICHIGAN STATE UNIVERSITY · PI WIERENGA, KATHRYN ALEXANDRIA · 2019 to 2021
$90k
NIEHS NIH HHS F31 ES030593NIEHS NIH HHS R01 ES027353NIEHS NIH HHS T32 ES007255
6 · The paper itself

Abstract

Repeated short-term intranasal instillation of lupus-prone mice with crystalline silica (cSiO

Indexed as

AnimalsAutoantibodiesAutoimmunityBronchoalveolar Lavage FluidChemokinesDietary SupplementsDisease Models, AnimalDocosahexaenoic AcidsFatty Acids, Omega-3FemaleGlomerulonephritisLungMicePneumoniaProteomeSilicon DioxideAutoantibodiesChemokinesDocosahexaenoic AcidsFatty Acids, Omega-3ProteomeSilicon Dioxideautoimmunitychemokineinflammationmetalloproteinaseomega-3 fatty acidsystemic lupus erythematosusTNF superfamily

Identifiers

PMID35126352
PMCPMC8813772
OpenAlexW4205184617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.