Evidence map›Paper›PMID 35126345›Full record

ArticleFrontiers in immunology2021

Predicting the Risk of Psoriatic Arthritis in Plaque Psoriasis Patients: Development and Assessment of a New Predictive Nomogram.

Panpan Liu, Yehong Kuang, Li Ye, Cong Peng, Wangqing Chen, Minxue Shen, Mi Zhang, Wu Zhu, Chengzhi Lv, Xiang Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  5. Pan-cancer and multiomics: advanced strategies for diagnosis, prognosis, and therapy in the complex genetic and molecular universe of cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
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  7. The role of SIRT1 in kidney diseases.International urology and nephrology · 2025
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  8. Review
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  12. The role of SWI/SNF complexes in digestive system neoplasms.Medical oncology (Northwood, London, England) · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Inflammation and Psoriasis: A Comprehensive Review.International journal of molecular sciences · 2023
    Review
  18. Artesunate targets cellular metabolism to regulate the Th17/Treg cell balance.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Panpan LiuThe Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.
Yehong KuangThe Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.
Li YeDalian Dermatosis Hospital, Dalian, China.
Cong PengThe Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.
Wangqing ChenThe Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.
Minxue ShenThe Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.
Mi ZhangThe Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.
Wu ZhuThe Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.
Chengzhi LvDalian Dermatosis Hospital, Dalian, China.
Xiang ChenThe Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNXiangya Hospital Central South University · CNDalian Dermatosis Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to develop a risk of psoriatic arthritis (PsA) predictive model for plaque psoriasis patients based on the available features. Methods: Patients with plaque psoriasis or PsA were recruited. The characteristics, skin lesions, and nail clinical manifestations of the patients have been collected. The least absolute shrinkage was used to optimize feature selection, and logistic regression analysis was applied to further select features and build a PsA risk predictive model. Calibration, discrimination, and clinical utility of the prediction model were evaluated by using the calibration plot, C-index, the area under the curve (AUC), and decision curve analysis. Internal validation was performed using bootstrapping validation. The model was subjected to external validation with two separate cohorts. Results: Age at onset, duration, nail involvement, erythematous lunula, onychorrhexis, oil drop, and subungual hyperkeratosis were presented as predictors to perform the prediction nomogram. The predictive model showed good calibration and discrimination (C-index: 0.759; 95% CI: 0.707-0.811). The AUC of this prediction model was 0.7578092. Excellent performances of the C-index were reached in the internal validation and external cohort validation (0.741, 0.844, and 0.845). The decision curve indicated good effect of the PsA nomogram in guiding clinical practice. Conclusion: This novel PsA nomogram could assess the risk of PsA in plaque psoriasis patients with good efficiency.

Indexed as

AdultArea Under CurveArthritis, PsoriaticCohort StudiesFemaleHumansMaleNomogramsPsoriasisRisk AssessmentRisk Factorsnail involvementnomogrampredictive modelpsoriasispsoriatic arthritis

Identifiers

PMID35126345
PMCPMC8810526
OpenAlexW4206005215

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.