Evidence map›Paper›PMID 35126280›Full record

SynthesisFrontiers in neurology2021

Surgical vs. Conservative Management for Lobar Intracerebral Hemorrhage, a Meta-Analysis of Randomized Controlled Trials.

Muhammad Junaid Akram, Rui Zhao, Xue Shen, Wen-Song Yang, Lan Deng, Zuo-Qiao Li, Xiao Hu, Li-Bo Zhao, Peng Xie, Qi Li

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Muhammad Junaid AkramDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Rui ZhaoDepartment of Neurology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Xue ShenDepartment of Neurology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Wen-Song YangDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Lan DengDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zuo-Qiao LiDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiao HuDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Li-Bo ZhaoDepartment of Neurology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Peng XieDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Qi LiDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chongqing Medical University · CNFirst Affiliated Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOutcomes regarding the conventional surgical and conservative treatment for the lobar intracerebral hemorrhage (ICH) have not been previously compared. The current meta-analysis was designed to review and compile the evidence regarding the management of patients with lobar intracerebral hemorrhage.

methodsOnline electronic databases, including PubMed, Embase, Medline, Cochrane Library, and Google Scholar, were searched for randomized controlled trials (RCTs). Studies were selected on the basis of the inclusion and exclusion criteria. Trials with CT-confirmed lobar intracerebral hemorrhage patients of which treatment regimen was started within 72 h following the stroke were included. Low quality trials were excluded. Death or dependence was defined as primary outcome and death at the end of the follow up was the secondary outcome.

resultsOne hundred five RCTs were screened and 96 articles were excluded on the basis of abstract. Nine articles were assessed for the eligibility and 7 trials were included that involved 1,102 patients. The Odds ratio (OR) for the primary outcome was 0.80 (95% CI, 0.62-1.04,

conclusionOur findings suggested that surgical treatments did not significantly improve the functional outcome as compared with the conservative medical management for patients with lobar ICH.

Indexed as

conservative managementintracerebral hemorrhagemeta-analysisrandomized controlled trialsurgical management

Identifiers

PMID35126280
PMCPMC8810825
OpenAlexW4206092823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.