ArticleFrontiers in psychiatry2021
Medication Adherence in a Cross-Diagnostic Sample of Patients From the Affective-to-Psychotic Spectrum: Results From the PsyCourse Study.
Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 51 citations in OpenAlex.
- Medication Dispensing Patterns Among Individuals With Serious Mental Illness Using a Remote Medication Dispensing and Adherence Monitoring Platform: Cohort Study.JMIR mental health · 2026Trial
- Consequences of Prolonged Substance Use Disorder in Psychosis, ADHD and Violence: 6 Month Follow-Up Study.Medical sciences (Basel, Switzerland) · 2026Article
- From fragmentation to integration: can social prescribing bridge the gap between multimorbidity and mental health in an ageing population?BMJ public health · 2026Review
- Community management: An effective model to reduce medication discontinuation rate in patients with schizophrenia.PloS one · 2026Article
- Associate the Socio Demographic Variables with Drug Compliance and Quality of Life among Patients with Affective Disorders.Journal of pharmacy & bioallied sciences · 2025Article
- Psychotropic medications adherence status and its determinants among older adults with severe affective and psychotic disorders: a multicenter cross-sectional study.Therapeutic advances in psychopharmacology · 2025Article
- Article
- Influencing factors of medication adherence in schizophrenic patients: a meta-analysis.Schizophrenia (Heidelberg, Germany) · 2023Article
- Medication adherence and cognitive performance in schizophrenia-spectrum and bipolar disorder: results from the PsyCourse Study.Translational psychiatry · 2023Article
- Bipolar Disorder and Polysubstance Use Disorder: Sociodemographic and Clinical Correlates.Frontiers in psychiatry · 2022Article
- Telemedicine as a Tool to Improve Medicine Adherence in Patients with Affective Disorders - A Systematic Literature Review.Patient preference and adherence · 2022Review
- Self-Reported Low Lithium Adherence Among Chinese Patients with Bipolar Disorder in Shenzhen: A Cross-Sectional Study.Patient preference and adherence · 2022Article
- Chronic Stress in Bipolar Disorders Across the Different Clinical States: Roles of HPA Axis and Personality.Neuropsychiatric disease and treatment · 2022Article
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Authors and funding
36 authors at 16 institutions in 6 countries.
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No grant is acknowledged in the PubMed record.
Abstract
introductionAccording to the World Health Organization, medication adherence is defined as the extent to which a person's behavior corresponds with an agreed recommendation from a healthcare provider. Approximately 50% of patients do not take their medication as prescribed, and non-adherence can contribute to the progress of a disease. For patients suffering from mental diseases non-adherence plays an important role. Various factors have been proposed as contributing to non-adherence, however the literature remains heterogeneous dependent on the analyzed patient subgroups. This study comprehensively evaluates the association of sociodemographic, clinical, personality and quality of life related factors with medication adherence by analyzing data from the PsyCourse study. The PsyCourse study is a large and cross-diagnostic cohort of psychiatric patients from the affective-to-psychotic spectrum.
methodsThe study sample comprised 1,062 patients from the PsyCourse study with various psychiatric diagnoses (mean [SD] age, 42.82 [12.98] years; 47.4% female). Data were analyzed to identify specific factors associated with medication adherence, and adherence was measured by a self-rating questionnaire. Odds ratios (OR) were estimated by a logistic regression for binary outcomes. Missing data were imputed using multiple imputation.
resultsThe following factors showed the strongest association with medication adherence: never having used illicit drugs (OR, 0.71), number of prescribed antipsychotics (OR, 1.40), the personality trait conscientiousness (OR, 1.26), and the environmental domain of quality of life (OR, 1.09).
conclusionIn a large and cross-diagnostic sample, we could show that a higher level of conscientiousness, a higher number of antipsychotic medication, a better quality of life within the environmental domain, and the absence of substance abuse contribute to a better medication adherence independent of the underlying disorder.
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