Evidence map›Paper›PMID 35126097›Full record

ReviewFrontiers in pharmacology2021

A Multivariate Approach to Ethnopharmacology: Antidiabetic Plants of Eeyou Istchee.

Braydon Hall, Michel Rapinski, Danielle Spoor, Hoda Eid, Ammar Saleem, John T Arnason, Brian Foster, Alain Cuerrier, Pierre S Haddad, Cory S Harris

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Braydon HallCanadian Institutes of Health Research (CIHR) Team in Aboriginal Anti-Diabetic Medicines, Montréal, QC, Canada.
Michel RapinskiCanadian Institutes of Health Research (CIHR) Team in Aboriginal Anti-Diabetic Medicines, Montréal, QC, Canada.
Danielle SpoorCanadian Institutes of Health Research (CIHR) Team in Aboriginal Anti-Diabetic Medicines, Montréal, QC, Canada.
Hoda EidCanadian Institutes of Health Research (CIHR) Team in Aboriginal Anti-Diabetic Medicines, Montréal, QC, Canada.
Ammar SaleemCanadian Institutes of Health Research (CIHR) Team in Aboriginal Anti-Diabetic Medicines, Montréal, QC, Canada.
John T ArnasonCanadian Institutes of Health Research (CIHR) Team in Aboriginal Anti-Diabetic Medicines, Montréal, QC, Canada.
Brian FosterCanadian Institutes of Health Research (CIHR) Team in Aboriginal Anti-Diabetic Medicines, Montréal, QC, Canada.
Alain CuerrierCanadian Institutes of Health Research (CIHR) Team in Aboriginal Anti-Diabetic Medicines, Montréal, QC, Canada.
Pierre S HaddadCanadian Institutes of Health Research (CIHR) Team in Aboriginal Anti-Diabetic Medicines, Montréal, QC, Canada.
Cory S HarrisCanadian Institutes of Health Research (CIHR) Team in Aboriginal Anti-Diabetic Medicines, Montréal, QC, Canada.
Canadian Institutes of Health Research · CAUniversité de Montréal · CAUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An ethnopharmacological metanalysis was conducted with a large database available on antidiabetic activities of plant foods and medicines from the northern boreal forest, which are traditionally used by the indigenous Cree of James Bay, Quebec, Canada. The objective was to determine which bioassays are closely associated with the traditional knowledge of the Cree and which pharmacological metrics and phytochemical signals best define these plants and their groups. Data from 17 plant species, ethnobotanically ranked by syndromic importance value for treatment of 15 diabetic symptoms, was used along with 49 bioassay endpoints reported across numerous pharmacological studies and a metabolomics dataset. Standardized activities were separated into primary, secondary and safety categories and summed to produce a Pharmacological Importance Value (PIV) in each of the three categories for each species. To address the question of which pharmacological metrics and phytochemical signals best define the CEI anti-diabetes plants, multivariate analyses were undertaken to determine groupings of plant families and plant parts. The analysis identified

Indexed as

diabetesindigenous knowledgein vitro bioassaysJames Bay Creemedicinal plants

Identifiers

PMID35126097
PMCPMC8808167
OpenAlexW4206051696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.