ReviewFrontiers in systems neuroscience2021
On the Importance of Being Flexible: Dynamic Brain Networks and Their Potential Functional Significances.
Review in Frontiers in systems neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Detecting neuroplastic effects induced by ketamine in healthy human subjects: A multimodal approach.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026Article
- Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease.Nature communications · 2026Article
- Functional connectivity dynamics of monoaminergic circuits related to fatigue in multiple sclerosis.Journal of neurology · 2026Article
- Regional and cannabis-related differences in prefrontal multiscale entropy of resting-state EEG.Clinical neurophysiology practice · 2026Article
- Intrinsic brain network dynamics modulated by neural stimulation to cerebellum.Network neuroscience (Cambridge, Mass.) · 2026Article
- Decoding the human brain during intelligence testing.Communications biology · 2025Article
- Dynamic structure-function coupling in macroscale neonatal brain networks.Communications biology · 2025Article
- Methylphenidate stabilizes dynamic brain network organization during tasks probing attention and reward processing in stimulant-naïve children with ADHD.Translational psychiatry · 2025Article
- Depression links to unstable resting-state brain dynamics: insights from hidden markov models and functional network variability.Psychological medicine · 2025Article
- Brain-Inspired Multisensory Learning: A Systematic Review of Neuroplasticity and Cognitive Outcomes in Adult Multicultural and Second Language Acquisition.Biomimetics (Basel, Switzerland) · 2025Review
- On the varieties of conscious experiences: Altered Beliefs Under Psychedelics (ALBUS).Neuroscience of consciousness · 2025Article
- Managing the tradeoff between reproduction and survival requires flexibility in behaviour and gene regulation in three-spined stickleback.Proceedings. Biological sciences · 2024Article
- Computational neurosciences and quantitative systems pharmacology: a powerful combination for supporting drug development in neurodegenerative diseases.Journal of pharmacokinetics and pharmacodynamics · 2024Review
- Sex differences in the flexibility of dynamic network reconfiguration of autism spectrum disorder based on multilayer network.Brain imaging and behavior · 2024Article
- The promise and pitfalls of a strength-based approach to child poverty and neurocognitive development: Implications for policy.Developmental cognitive neuroscience · 2024Article
- As without, so within: how the brain's temporo-spatial alignment to the environment shapes consciousness.Interface focus · 2023Article
- Pattern breaking: a complex systems approach to psychedelic medicine.Neuroscience of consciousness · 2023Article
- Increased flexibility of brain dynamics in patients with multiple sclerosis.Brain communications · 2023Article
- Human electromagnetic and haemodynamic networks systematically converge in unimodal cortex and diverge in transmodal cortex.PLoS biology · 2022Article
- Integrated world modeling theory expanded: Implications for the future of consciousness.Frontiers in computational neuroscience · 2022Article
Corrections and comments
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Authors and funding
3 authors.
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Abstract
In this theoretical review, we begin by discussing brains and minds from a dynamical systems perspective, and then go on to describe methods for characterizing the flexibility of dynamic networks. We discuss how varying degrees and kinds of flexibility may be adaptive (or maladaptive) in different contexts, specifically focusing on measures related to either more disjoint or cohesive dynamics. While disjointed flexibility may be useful for assessing neural entropy, cohesive flexibility may potentially serve as a proxy for self-organized criticality as a fundamental property enabling adaptive behavior in complex systems. Particular attention is given to recent studies in which flexibility methods have been used to investigate neurological and cognitive maturation, as well as the breakdown of conscious processing under varying levels of anesthesia. We further discuss how these findings and methods might be contextualized within the Free Energy Principle with respect to the fundamentals of brain organization and biological functioning more generally, and describe potential methodological advances from this paradigm. Finally, with relevance to computational psychiatry, we propose a research program for obtaining a better understanding of ways that dynamic networks may relate to different forms of psychological flexibility, which may be the single most important factor for ensuring human flourishing.
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