Evidence map›Paper›PMID 35126040›Full record

ReviewFrontiers in neuroscience2021

Targeting Sensory and Motor Integration for Recovery of Movement After CNS Injury.

Ahmet S Asan, James R McIntosh, Jason B Carmel

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Hindlimb Representation in the Spiny Mouse Sensorimotor Cortex.The Journal of comparative neurology · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. A stuttering-associatedbioRxiv : the preprint server for biology · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ahmet S AsanDepartments of Neurology and Orthopedics, Columbia University, New York, NY, United States.
James R McIntoshDepartments of Neurology and Orthopedics, Columbia University, New York, NY, United States.
Jason B CarmelDepartments of Neurology and Orthopedics, Columbia University, New York, NY, United States.
Columbia University · US

Funding

Spinal Cord Associative PlasticityR01NS124224 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CARMEL, JASON BRANT, HAREL, NOAM Y. · 2021 to 2025
$3.3M
Paired Brain and Spinal Cord Stimulation to Strengthen Spinal Sensorimotor CircuitsR01NS115470 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CARMEL, JASON BRANT · 2021 to 2025
$2.7M
NINDS NIH HHS R01 NS115470NINDS NIH HHS R01 NS124224
6 · The paper itself

Abstract

The central nervous system (CNS) integrates sensory and motor information to acquire skilled movements, known as sensory-motor integration (SMI). The reciprocal interaction of the sensory and motor systems is a prerequisite for learning and performing skilled movement. Injury to various nodes of the sensorimotor network causes impairment in movement execution and learning. Stimulation methods have been developed to directly recruit the sensorimotor system and modulate neural networks to restore movement after CNS injury. Part 1 reviews the main processes and anatomical interactions responsible for SMI in health. Part 2 details the effects of injury on sites critical for SMI, including the spinal cord, cerebellum, and cerebral cortex. Finally, Part 3 reviews the application of activity-dependent plasticity in ways that specifically target integration of sensory and motor systems. Understanding of each of these components is needed to advance strategies targeting SMI to improve rehabilitation in humans after injury.

Indexed as

motor cortexmovement recoverypaired stimulationplasticitysensorimotor integration (SMI)spinal cord

Identifiers

PMID35126040
PMCPMC8813971
OpenAlexW4205211658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.