Evidence map›Paper›PMID 35126039›Full record

ArticleFrontiers in neuroscience2021

Altered Neurovascular Coupling in Unilateral Pulsatile Tinnitus.

Xiaoshuai Li, Ning Xu, Chihang Dai, Xuxu Meng, Xiaoyu Qiu, Heyu Ding, Rong Zeng, Han Lv, Pengfei Zhao, Zhenghan Yang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Xiaoshuai LiDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Ning XuDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Chihang DaiDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Xuxu MengDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Xiaoyu QiuDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Heyu DingDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Rong ZengDepartment of Otolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Han LvDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Pengfei ZhaoDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Zhenghan YangDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Shusheng GongDepartment of Otolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Zhenchang WangDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Capital Medical University · CNBeijing Friendship Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAltered cerebral blood flow (CBF) and regional homogeneity (ReHo) have been reported in pulsatile tinnitus (PT) patients. We aimed to explore regional neurovascular coupling changes in PT patients. MATERIALS AND

methodsTwenty-four right PT patients and 25 sex- and age-matched normal controls were included in this study. All subjects received arterial spin labeling imaging to measure CBF and functional MRI to compute ReHo. CBF/ReHo ratio was used to assess regional neurovascular coupling between the two groups. We also analyzed the correlation between CBF/ReHo ratio and clinical data from the PT patients.

resultsPT patients exhibited increased CBF/ReHo ratio in left middle temporal gyrus and right angular gyrus than normal controls, and no decreased CBF/ReHo ratio was found. CBF/ReHo ratio in the left middle temporal gyrus of PT patients was positively correlated with Tinnitus Handicap Inventory score (

conclusionThese findings indicated that patients with PT exhibit abnormal neurovascular coupling, which provides new information for understanding the neuropathological mechanisms underlying PT.

Indexed as

arterial spin labelingcerebral blood flowfunctional magnetic resonance imagingpulsatile tinnitusregional homogeneity

Identifiers

PMID35126039
PMCPMC8815060
OpenAlexW4206989223

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.