Evidence map›Paper›PMID 35125873›Full record

ArticleInternational journal of tryptophan research : IJTR2022

Activation of the Kynurenine Pathway and Production of Inflammatory Cytokines by Astrocytes and Microglia Infected With

Deivison Silva Argolo, Julita Maria Pereira Borges, Luciana Dos Santos Freitas, Gizelle Alves Pina, Maria Socorro Grangeiro, Victor Diógenes Amaral da Silva, Alexandre Moraes Pinheiro, Rodrigo Souza Conceição, Alexsandro Branco, Gilles Guillemin and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of tryptophan research : IJTR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Deivison Silva ArgoloLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.
Julita Maria Pereira BorgesLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.
Luciana Dos Santos FreitasLaboratory of Biochemistry and Veterinary Immunology Federal University of Recôncavo of Bahia, Brazil.
Gizelle Alves PinaLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.
Maria Socorro GrangeiroLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.
Victor Diógenes Amaral da SilvaLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.
Alexandre Moraes PinheiroLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.
Rodrigo Souza ConceiçãoLaboratory of Phytochemistry, Department of Health, State University of Feira de Santana (UEFS), Brazil.ORCID https://orcid.org/0000-0003-3625-9535
Alexsandro BrancoLaboratory of Phytochemistry, Department of Health, State University of Feira de Santana (UEFS), Brazil.
Gilles GuilleminNeuroinflammation Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.ORCID https://orcid.org/0000-0001-8105-4470
Silvia Lima CostaLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.ORCID https://orcid.org/0000-0002-8975-3871
Maria de Fátima Dias CostaLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia (UFBA); National Institute of Translational Neuroscience (INCT-CNPq), Brazil.
National Council for Scientific and Technological Development · BRUniversidade Estadual de Feira de Santana · BRMacquarie University · AUUniversidade Federal do Recôncavo da Bahia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the central nervous system, astrocytes and microglia contribute to homeostasis, regulating the immune response to infectious agents.

Indexed as

gliaKynurenineNeospora caninumneuroinflammation

Identifiers

PMID35125873
PMCPMC8808026
OpenAlexW4210570139

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.