Evidence map›Paper›PMID 35125812›Full record

ArticleChinese journal of cancer research = Chung-kuo yen cheng yen chiu2021

Deep learning model improves radiologists' performance in detection and classification of breast lesions.

Yingshi Sun, Yuhong Qu, Dong Wang, Yi Li, Lin Ye, Jingbo Du, Bing Xu, Baoqing Li, Xiaoting Li, Kexin Zhang and 8 more

Abstract read
In one paragraph

Article in Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Artificial intelligence in mammography: a systematic review of the external validation.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2024
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Yingshi SunKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiology, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Yuhong QuKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiology, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Dong WangKey Laboratory of Machine Perception, MOE, School of EECS, Peking University, Beijing 100871, China.
Yi LiDepartment of Radiology, Shunyi Women's & Children's Hospital of Beijing Children's Hospital, Beijing 101399, China.
Lin YeDepartment of Radiology, Beijing Chaoyang Maternal and Child Health Center, Beijing 122099, China.
Jingbo DuDepartment of Radiology, Beijing Daxing District People's Hospital, Beijing 102699, China.
Bing XuDepartment of Radiology, Shunyi District Hospital, Beijing 101312, China.
Baoqing LiDepartment of Medical Imaging, Beijing Shijingshan Hospital, Beijing 100040, China.
Xiaoting LiKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiology, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Kexin ZhangKey Laboratory of Machine Perception, MOE, School of EECS, Peking University, Beijing 100871, China.
Yanjie ShiKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiology, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Ruijia SunKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiology, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Yichuan WangCenter for Data Science, Peking University, Beijing 100871, China.
Rong LongKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiology, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Dengbo ChenCenter for Data Science, Peking University, Beijing 100871, China.
Haijiao LiKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiology, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Liwei WangKey Laboratory of Machine Perception, MOE, School of EECS, Peking University, Beijing 100871, China.
Min CaoKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiology, Peking University Cancer Hospital & Institute, Beijing 100142, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveComputer-aided diagnosis using deep learning algorithms has been initially applied in the field of mammography, but there is no large-scale clinical application.

methodsThis study proposed to develop and verify an artificial intelligence model based on mammography. Firstly, mammograms retrospectively collected from six centers were randomized to a training dataset and a validation dataset for establishing the model. Secondly, the model was tested by comparing 12 radiologists' performance with and without it. Finally, prospectively enrolled women with mammograms from six centers were diagnosed by radiologists with the model. The detection and diagnostic capabilities were evaluated using the free-response receiver operating characteristic (FROC) curve and ROC curve.

resultsThe sensitivity of model for detecting lesions after matching was 0.908 for false positive rate of 0.25 in unilateral images. The area under ROC curve (AUC) to distinguish the benign lesions from malignant lesions was 0.855 [95% confidence interval (95% CI): 0.830, 0.880]. The performance of 12 radiologists with the model was higher than that of radiologists alone (AUC: 0.852

conclusionsThe artificial intelligence model exhibits high accuracy for detecting and diagnosing breast lesions, improves diagnostic accuracy and saves time.

Indexed as

artificial intelligenceBreast cancerdeep learningmammography

Identifiers

PMID35125812
PMCPMC8742176

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.