Evidence map›Paper›PMID 35125708›Full record

ArticleIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion2022

Comparison Between CHOP and DAEPOCH with or Without Rituximab in Adult High Grade B Cell Lymphoma, Not Otherwise Specified; A Retrospective Study From a Tertiary Cancer Hospital in South India.

Lalatendu Moharana, Lokanatha Dasappa, Suresh Babu, K N Lokesh, Ah Rudresh, L K Rajeev, Smitha Saldanha, Kanika Sharma, Linu Abraham Jacob

Open access · greenAbstract read
In one paragraph

Article in Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lalatendu MoharanaDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Dr MH Marigowda Road, Bengaluru, Karnataka 560029 India.
Lokanatha DasappaDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Dr MH Marigowda Road, Bengaluru, Karnataka 560029 India.
Suresh BabuDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Dr MH Marigowda Road, Bengaluru, Karnataka 560029 India.
K N LokeshDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Dr MH Marigowda Road, Bengaluru, Karnataka 560029 India.
Ah RudreshDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Dr MH Marigowda Road, Bengaluru, Karnataka 560029 India.
L K RajeevDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Dr MH Marigowda Road, Bengaluru, Karnataka 560029 India.
Smitha SaldanhaDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Dr MH Marigowda Road, Bengaluru, Karnataka 560029 India.
Kanika SharmaDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Dr MH Marigowda Road, Bengaluru, Karnataka 560029 India.
Linu Abraham JacobDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Dr MH Marigowda Road, Bengaluru, Karnataka 560029 India.ORCID 0000-0002-5806-1004
Kidwai Memorial Institute of Oncology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphoma that on morphology appear blastoid or intermediate between DLBCL and BL but who lack myc and bcl-2 and/or bcl-6 rearrangements are grouped under high grade B-cell lymphoma, not otherwise specified (HGBL, NOS). Only a few studies have yet compared the outcome of HGBL, NOS treated with different chemo-immunotherapy regimens. HGBL, NOS patients were analyzed retrospectively, who were treated with CHOP or DAEPOCH regimens every 21 days for six cycles with or without rituximab. The primary clinical objective was progression free survival. One and two year PFS rates were 29.4% and 20.6% for the CHOP arm and, 65.2% and 47.8% for the DAEPOCH arm respectively. There was statistically significant difference in mean PFS between the arms (DAEPOCH vs CHOP: 19.7 months vs 12.8 months; HR = 0.44,

Indexed as

CHOPDAEPOCHHigh grade B-cell lymphoma

Identifiers

PMID35125708
PMCPMC8804013
OpenAlexW3144452350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.