Evidence map›Paper›PMID 35125173›Full record

ReviewFertility and sterility2022

What advances may the future bring to the diagnosis, treatment, and care of male sexual and reproductive health?

Christopher L R Barratt, Christina Wang, Elisabetta Baldi, Igor Toskin, James Kiarie, Dolores J Lamb, other Editorial Board Members of the WHO Laboratory Manual for the Examination and Processing of Human Semen

Open access · hybridAbstract readReview
In one paragraph

Review in Fertility and sterility, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Male infertility.Nature reviews. Disease primers · 2023
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Christopher L R BarrattDivision of Systems Medicine, University of Dundee Medical School, Ninewells Hospital, Dundee, Scotland. Electronic address: c.barratt@dundee.ac.uk.
Christina WangClinical and Translational Science Institute, The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California.
Elisabetta BaldiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Igor ToskinDepartment of Sexual and Reproductive Health and Research, World Health Organization, Geneva, Switzerland.
James KiarieDepartment of Sexual and Reproductive Health and Research, World Health Organization, Geneva, Switzerland.
Dolores J LambThe James Buchanan Brady Foundation Department of Urology, Center for Reproductive Genomics and Englander Institute for Personalized Medicine, Weill Cornell Medical College, New York, New York.
other Editorial Board Members of the WHO Laboratory Manual for the Examination and Processing of Human SemenOther Editorial Board Members and Contributors of the WHO Laboratory Manual for the Examination and Processing of Human Semen 6th edition.
World Health Organization · CHCornell University · USHarbor–UCLA Medical Center · USUniversity of Dundee · GBUniversity of Florence · IT

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Preclinical testing of a novel non-hormonal intravaginal ring to prevent pregnancy and sexually transmitted infectionsP50HD106793 · NICHD · POPULATION COUNCIL · PI FRIEDLAND, BARBARA A · 2021 to 2025
$11.1M
Mechanism Underlying the Transduction of Epimutations from the Soma to the Male GermlineP50HD098593 · NICHD · UNIVERSITY OF NEVADA RENO · PI SWERDLOFF, RONALD SHERWIN · 2019 to 2024
$7.2M
Targeting sperm-specific proteins during meiosis and sperm morphogenesisP01HD087157 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MATZUK, MARTIN M. · 2017 to 2021
$6.2M
Optimization and pre-clinical evaluation of ADCY10 inhibitorsP50HD100549 · NICHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI BUCK, JOCHEN, LEVIN, LONNY R · 2019 to 2021
$6.0M
Improving the Diagnosis of Congenital Genitourinary Defects.R01DK078121 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI LAMB, DOLORES JEAN · 2007 to 2021
$4.8M
FUNCTIONAL GENOMICS AND PROTEOMICS TO REVEAL REPRODUCTIVE-TRACT SPECIFIC PROTEINSR01HD095341 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI GARCIA, THOMAS · 2018 to 2020
$1.2M
Chief Scientist OfficeNCATS NIH HHS UL1 TR001881NICHD NIH HHS HHSN275200800044UNICHD NIH HHS P01 HD087157NICHD NIH HHS P50 HD098593NICHD NIH HHS P50 HD100549NICHD NIH HHS P50 HD106793NICHD NIH HHS R01 HD095341NIDDK NIH HHS R01 DK078121World Health Organization 001
6 · The paper itself

Abstract

Over the past 40 years, since the publication of the original WHO Laboratory Manual for the Examination and Processing of Human Semen, the laboratory methods used to evaluate semen markedly changed and benefited from improved precision and accuracy, as well as the development of new tests and improved, standardized methodologies. Herein, we present the impact of the changes put forth in the sixth edition together with our views of evolving technologies that may change the methods used for the routine semen analysis, up-and-coming areas for the development of new procedures, and diagnostic approaches that will help to extend the often-descriptive interpretations of several commonly performed semen tests that promise to provide etiologies for the abnormal semen parameters observed. As we look toward the publication of the seventh edition of the manual in approximately 10 years, we describe potential advances that could markedly impact the field of andrology in the future.

Indexed as

Infertility, MaleAndrologyDiffusion of InnovationFertilityForecastingGenetic TestingGenomicsHumansMaleMen's HealthReproductionReproductive HealthSemen AnalysisSexual BehaviorSexual HealthgenesmotilitySemen analysissperm morphology

Identifiers

PMID35125173
PMCPMC8877074
OpenAlexW4210569276

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.