ArticleMicrobiome2022
The crewed journey to Mars and its implications for the human microbiome.
Article in Microbiome, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- An early microbial landscape: inspiring endeavor from the China Space Station Habitation Area Microbiome Program (CHAMP).Science China. Life sciences · 2025Article
- Food fermentation in space: Opportunities and challenges.iScience · 2025Article
- Special Issue: 'Advances in Space Biology'.Life (Basel, Switzerland) · 2024Article
- Microbiome in a ground-based analog cabin of China Space Station during a 50-day human occupation.ISME communications · 2024Article
- Article
- Solar ultraviolet light collector for germicidal irradiation on the moon.Scientific reports · 2023Article
- Addressing Spaceflight Biology through the Lens of a Histologist-Embryologist.Life (Basel, Switzerland) · 2023Review
- Microbiota and probiotics: chances and challenges - a symposium report.Gut microbiome (Cambridge, England) · 2023Review
- Long-Duration Space Travel Support Must Consider Wider Influences to Conserve Microbiota Composition and Function.Life (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A human spaceflight to Mars is scheduled for the next decade. In preparation for this unmatched endeavor, a plethora of challenges must be faced prior to the actual journey to Mars. Mission success will depend on the health of its crew and its working capacity. Hence, the journey to Mars will also depend on the microbiome and its far-reaching effects on individual crew health, the spaceship's integrity, and food supply. As human beings rely on their microbiome, these microbes are essential and should be managed to ensure their beneficial effects outweigh potential risks. In this commentary, we focus on the current state of knowledge regarding a healthy (gut) microbiome of space travelers based on research from the International Space Station and simulation experiments on Earth. We further indicate essential knowledge gaps of microbial conditions during long-term space missions in isolated confined space habitats or outposts and give detailed recommendations for microbial monitoring during pre-flight, in-flight, and post-flight. Finally, the conclusion outlines open questions and aspects of space traveler's health beyond the scope of this commentary. Video Abstract.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.