Evidence map›Paper›PMID 35124700›Full record

GuidelineSpinal cord2022

The CanPain SCI clinical practice guidelines for rehabilitation management of neuropathic pain after spinal cord injury: 2021 update.

Eldon Loh, Magdalena Mirkowski, Alexandria Roa Agudelo, David J Allison, Brooke Benton, Thomas N Bryce, Sara Guilcher, Tara Jeji, Anna Kras-Dupuis, Denise Kreutzwiser and 14 more

2 registry-linked trialsAbstract readPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Spinal cord, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 42 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06463418 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Exoskeleton Training for Spinal Cord Injury Neuropathic Pain (ExSCIP): Protocol for a Phase 2 Feasibility Randomised Trial

TypeinterventionalSponsorUniversity College DublinRan2024 to 2026Enrolled40ConditionsTraumatic Spinal Cord InjuryArmsEkoskeleton (Intervention), Relaxation (Comparator)
NCT07254767 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Combination of Visuo-proprioceptive Virtual Walking and Neuromodulation to Reduce Neuropathic Pain in Individuals With Spinal Cord Injury

TypeinterventionalSponsorCentre for Interdisciplinary Research in Rehabilitation of Greater MontrealRan2025 to 2027Enrolled10ConditionsNeuropathic PainArmsTranscranial Direct Current Stimulation (tDCS) combined with virtual reality and muscle vibration
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  3. Efficacy of neuromodulation and rehabilitation approaches on pain relief in patients with spinal cord injury: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Eldon LohLawson Health Research Institute, London, ON, Canada. Eldon.Loh@sjhc.london.on.ca.
Magdalena MirkowskiLawson Health Research Institute, London, ON, Canada.ORCID http://orcid.org/0000-0001-6263-7750
Alexandria Roa AgudeloLawson Health Research Institute, London, ON, Canada.
David J AllisonLawson Health Research Institute, London, ON, Canada.
Brooke BentonIcahn School of Medicine at Mount Sinai, New York City, NY, USA.
Thomas N BryceIcahn School of Medicine at Mount Sinai, New York City, NY, USA.
Sara GuilcherUniversity of Toronto, Toronto, ON, Canada.ORCID http://orcid.org/0000-0002-9552-9139
Tara JejiOntario Neurotrauma Foundation, Toronto, ON, Canada.
Anna Kras-DupuisParkwood Institute, London, ON, Canada.
Denise KreutzwiserSt Joseph's Health Care Pain Management Program, London, ON, Canada.ORCID http://orcid.org/0000-0001-9207-9104
Oda LaniziSCI-Ontario, Toronto, ON, Canada.
Gary Lee-Tai-FuyParkwood Institute, London, ON, Canada.
James W MiddletonJohn Walsh Centre for Rehabilitation Research, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0002-2777-8619
Dwight E MoulinWestern University, London, ON, Canada.
Colleen O'ConnellStan Cassidy Centre for Rehabilitation, Fredericton, NB, Canada.
Steve OrenczukParkwood Institute, London, ON, Canada.
Patrick PotterParkwood Institute, London, ON, Canada.
Christine ShortDalhousie University, Halifax, NS, Canada.
Robert TeasellLawson Health Research Institute, London, ON, Canada.
Andrea TownsonUniversity of British Columbia, Vancouver, BC, Canada.
Eva Widerström-NogaThe Miami Project, Miami, FL, USA.
Dalton L WolfeLawson Health Research Institute, London, ON, Canada.
Nancy XiaSCI-Ontario, Toronto, ON, Canada.
Swati MehtaLawson Health Research Institute, London, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designClinical practice guidelines.

objectivesThe objective was to update the 2016 version of the Canadian clinical practice guidelines for the management of neuropathic pain in people with spinal cord injury (SCI).

settingThe guidelines are relevant for inpatient, outpatient and community SCI rehabilitation settings in Canada.

methodsThe guidelines were updated in accordance with the Appraisal of Guidelines for Research and Evaluation II tool. A Steering Committee and Working Group reviewed the relevant evidence on neuropathic pain management (encompassing screening and diagnosis, treatment and models of care) after SCI. The quality of evidence was scored using Grading of Recommendations Assessment, Development and Evaluation (GRADE). A consensus process was followed to achieve agreement on recommendations and clinical considerations.

resultsThe working group identified and reviewed 46 additional relevant articles published since the last version of the guidelines. The panel agreed on 3 new screening and diagnosis recommendations and 8 new treatment recommendations. Two key changes to these treatment recommendations included the introduction of general treatment principles and a new treatment recommendation classification system. No new recommendations to model of care were made.

conclusionsThe CanPainSCI recommendations for the management of neuropathic pain after SCI should be used to inform practice.

Indexed as

NeuralgiaSpinal Cord InjuriesCanadaConsensusHumans

Identifiers

PMID35124700
PMCPMC9209331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.