Evidence map›Paper›PMID 35124370›Full record

SynthesisMedical image analysis2022

Medical image analysis on left atrial LGE MRI for atrial fibrillation studies: A review.

Lei Li, Veronika A Zimmer, Julia A Schnabel, Xiahai Zhuang

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Medical image analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. mCardiacDx: Radar-Driven Contactless Monitoring and Diagnosis of Atrial Fibrillation.IEEE journal of translational engineering in health and medicine · 2026
    Article
  5. Assessment of Left Atrial Fibrosis With Cardiac MRI.Journal of magnetic resonance imaging : JMRI · 2025
    Article
  6. Article
  7. Article
  8. Investigating the Domain Adaptability of General-Purpose Foundation Models for Left Atrium Segmentation from MR Images.Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH (Conference) · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. LASSNet: A Four Steps Deep Neural Network for Left Atrial Segmentation and Scar Quantification.Left atrial and scar quantification and segmentation : first challenge, LAScarQS 2022 held in conjunction with MICCAI 2022, Singapore, September 18, 2022, proceedings · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Lei LiSchool of Data Science, Fudan University, Shanghai, China; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China; School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Veronika A ZimmerSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK; Department of Informatics, Technical University of Munich, Germany.
Julia A SchnabelSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK; Department of Informatics, Technical University of Munich, Germany; Helmholtz Center Munich, Germany.
Xiahai ZhuangSchool of Data Science, Fudan University, Shanghai, China. Electronic address: zxh@fudan.edu.cn.
Fudan University · CNHelmholtz Zentrum München · DEKing's College London · GBShanghai Jiao Tong University · CN

Funding

British Heart Foundation TA/F/20/210021Wellcome Trust 102431Wellcome Trust 203148Wellcome Trust 203148/Z/16/ZWellcome Trust WT 102431Wellcome Trust WT 203148/Z/16/Z
6 · The paper itself

Abstract

Late gadolinium enhancement magnetic resonance imaging (LGE MRI) is commonly used to visualize and quantify left atrial (LA) scars. The position and extent of LA scars provide important information on the pathophysiology and progression of atrial fibrillation (AF). Hence, LA LGE MRI computing and analysis are essential for computer-assisted diagnosis and treatment stratification of AF patients. Since manual delineations can be time-consuming and subject to intra- and inter-expert variability, automating this computing is highly desired, which nevertheless is still challenging and under-researched. This paper aims to provide a systematic review on computing methods for LA cavity, wall, scar, and ablation gap segmentation and quantification from LGE MRI, and the related literature for AF studies. Specifically, we first summarize AF-related imaging techniques, particularly LGE MRI. Then, we review the methodologies of the four computing tasks in detail and summarize the validation strategies applied in each task as well as state-of-the-art results on public datasets. Finally, the possible future developments are outlined, with a brief survey on the potential clinical applications of the aforementioned methods. The review indicates that the research into this topic is still in the early stages. Although several methods have been proposed, especially for the LA cavity segmentation, there is still a large scope for further algorithmic developments due to performance issues related to the high variability of enhancement appearance and differences in image acquisition.

Indexed as

Atrial FibrillationGadoliniumCicatrixContrast MediaHeart AtriaHumansMagnetic Resonance ImagingContrast MediaGadoliniumAtrial fibrillationLeft atriumLGE MRIReview

Identifiers

PMID35124370
PMCPMC7614005
OpenAlexW4220812427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.