Evidence map›Paper›PMID 35123809›Full record

ArticleArchives of medical research2022

A Multimodal Strategy to Reduce the Risk of Hospitalization/death in Ambulatory Patients with COVID-19.

Iván de Jesús Ascencio-Montiel, Juan Carlos Tomás-López, Verónica Álvarez-Medina, Luisa Estela Gil-Velázquez, Hortensia Vega-Vega, Héctor Raúl Vargas-Sánchez, Manuel Cervantes-Ocampo, Miguel Ángel Villasís-Keever, Cesar Raúl González-Bonilla, Célida Duque-Molina

Abstract read
In one paragraph

Article in Archives of medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Iván de Jesús Ascencio-MontielCoordinación de Vigilancia Epidemiológica, Unidad de Planeación e Innovación en Salud, Dirección de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Juan Carlos Tomás-LópezDivisión de Medicina Familiar, Coordinación de Unidades de Primer Nivel, Unidad de Atención Médica, Dirección de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Verónica Álvarez-MedinaDivisión de Medicina Familiar, Coordinación de Unidades de Primer Nivel, Unidad de Atención Médica, Dirección de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Luisa Estela Gil-VelázquezDivisión de Medicina Familiar, Coordinación de Unidades de Primer Nivel, Unidad de Atención Médica, Dirección de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Hortensia Vega-VegaDivisión de Medicina Familiar, Coordinación de Unidades de Primer Nivel, Unidad de Atención Médica, Dirección de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Héctor Raúl Vargas-SánchezDivisión de Medicina Familiar, Coordinación de Unidades de Primer Nivel, Unidad de Atención Médica, Dirección de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Manuel Cervantes-OcampoCoordinación de Unidades de Primer Nivel, Unidad de Atención Médica, Dirección de Prestaciones Médicas Instituto Mexicano del Seguro Social, Ciudad de México, México.
Miguel Ángel Villasís-KeeverUnidad de Investigación en Análisis y Síntesis de la Evidencia, Coordinación de Investigación en Salud, Unidad de Educación e Investigación, Dirección de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Ciudad de México, México.
Cesar Raúl González-BonillaUnidad de Investigación en Análisis y Síntesis de la Evidencia, Coordinación de Investigación en Salud, Unidad de Educación e Investigación, Dirección de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Ciudad de México, México; Coordinación de Investigación en Salud, Unidad de Educación e Investigación, Dirección de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Ciudad de México, México. Electronic address: c.gonzalez.bonilla@gmail.com.
Célida Duque-MolinaDirección de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Ciudad de México, México.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDifferent interventions have been implemented worldwide for the house-hold monitoring of patients with mild COVID-19 to reduce the burden of healthcare systems and guarantee quality of care. Telephone follow up and treatment kits have not been evaluated in the context of a national-wide primary care program. AIM OF THE STUDY: To compare the risk of hospitalization and death for COVID-19 between ambulatory patients who received and those who did not receive a treatment kit and telephone follow-up in a developing country

methodsA two-group comparative analysis was conducted using data from the medical information systems of the Mexican Institute of Social Security. We included a total of 28,048 laboratory-confirmed SARS-CoV-2 patients: 7,898 (28.2%) received a medical kit and 20,150 (71.8%) did not. The incidence rates of hospitalization and death combined were calculated. To identify significant associations between hospitalization or death and treatment medical kits, we calculated the risk ratios using a multivariate logistic model.

resultsThe incidence of hospitalization was 6.14% in patients who received a kit and 11.71% in those who did not. Male sex, age, and a medical history of obesity, hypertension, diabetes, immunosuppression, or kidney disease were associated with increased risk of hospitalization or death. The risk rates were reduced in patients who received a medical kit or telephone follow-up. In the multivariate model, receiving a medical kit was associated with a lower risk of hospitalization or death from COVID-19: adjusted risk ratio 0.41 (95% confidence interval 0.36-0.47).

conclusionUse of a multimodal strategy may reduce the risk of hospitalization and death in adult outpatients with mild COVID-19.

Indexed as

COVID-19Kidney DiseasesAdultFemaleHospitalizationHumansIncidenceMaleSARS-CoV-2Ambulatory managementCOVID-19IvermectinSARS-Cov-2Telemedicine

Identifiers

PMID35123809
PMCPMC8784438

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.