Evidence map›Paper›PMID 35123768›Full record

ArticleAmerican journal of surgery2022

Impact of the 2015 American thyroid association guidelines on treatment in older adults with low-risk, differentiated thyroid cancer.

Whitney Sutton, Philip K Crepeau, Joseph K Canner, Shkala Karzai, Dorry L Segev, Aarti Mathur

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Whitney SuttonDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Philip K CrepeauDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Joseph K CannerDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Shkala KarzaiDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Dorry L SegevDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Aarti MathurDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: amathu10@jhmi.edu.
Johns Hopkins University · US

Funding

Clinical and Laboratory Research Training for Surgical OncologistsT32CA126607 · NCI · JOHNS HOPKINS UNIVERSITY · PI CAMERON, ANDREW M. · 2008 to 2024
$6.0M
Association of Fraility with Post thyroidectomy alterations in Voice, Swallowing, and Quality of LifeK23AG053429 · NIA · JOHNS HOPKINS UNIVERSITY · PI MATHUR, AARTI · 2017 to 2022
$1.0M
Patient Oriented Research in Solid Organ TransplantationK24AI144954 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SEGEV, DORRY L. · 2020 to 2024
$956k
NCI NIH HHS T32 CA126607NIAID NIH HHS K24 AI144954NIA NIH HHS K23 AG053429
6 · The paper itself

Abstract

backgroundThe impact of the 2015 ATA guidelines on treatment for differentiated thyroid cancer (DTC) in older adults is unclear.

methods60,567 adults (age≥18) with low-risk DTC diagnosed between 2010 and 2018 were identified using SEER-21. Annual rates of total thyroidectomy (TT), hemithyroidectomy (HT), and active surveillance (AS) were analyzed using interrupted time series stratified by age: younger adults (18-64), older adults (65-79), and the super-elderly (≥80).

resultsAfter 2015, annual rates of TT decreased by 2.6% and 1.9% in younger and older adults (p < 0.001), but increased by 4.6% in the super-elderly (p = 0.0126). Annual rates of HT increased by 2.6% and 1.7% in younger and older adults (p < 0.001), but decreased by 3.8% in the super-elderly (p = 0.0029). Older adults and the super-elderly were more likely than younger adults to undergo HT (aOR = 1.1, 95% CI: 1.03-1.2, p = 0.002 and aOR = 1.5, 95% CI: 1.3-1.7, p < 0.001) and AS (aOR = 1.5, 95% CI: 1.4-1.7, p < 0.001 and aOR = 6.5, 95% CI: 5.4-7.7, p < 0.001) when compared to TT following 2015.

conclusionsTreatment of DTC continues to vary significantly among age groups.

Indexed as

AdenocarcinomaThyroid NeoplasmsAdolescentAgedHumansThyroidectomyUnited StatesActive surveillanceATA guidelinesHemithyroidectomyOlder adultsThyroid cancerThyroidectomy

Identifiers

PMID35123768
PMCPMC9232901
OpenAlexW4210705555

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.