Evidence map›Paper›PMID 35123425›Full record

ArticleBMC infectious diseases2022

Gaps in the congenital syphilis prevention cascade: qualitative findings from Kern County, California.

Eunhee Park, Julie Yip, Emily Harville, Marlene Nelson, Gloria Giarratano, Pierre Buekens, Jennifer Wagman

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. State-of-the-Art Review: Congenital Syphilis in the Modern Era: Current Strategies and Future Directions.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Social Factors Associated With Congenital Syphilis in Missouri.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Eunhee ParkDepartment of Community Health Sciences, UCLA Fielding School of Public Health, 650 Charles E. Young Drive South, Los Angeles, CA, 90095, USA. eepark@g.ucla.edu.
Julie YipDepartment of Bioengineering, UCSD Jacobs School of Engineering, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Emily HarvilleDepartment of Epidemiology, Tulane School of Public Health and Tropical Medicine, 1440 Canal St. #8318, New Orleans, LA, 70112, USA.
Marlene NelsonPartners in Care Foundation, 5251 Office Park Dr, Bakersfield, CA, 93309, USA.
Gloria GiarratanoSchool of Nursing, Louisiana State University Health Sciences Center, New Orleans, LA, 70112, USA.
Pierre BuekensDepartment of Epidemiology, Tulane School of Public Health and Tropical Medicine, 1440 Canal St. #8318, New Orleans, LA, 70112, USA.
Jennifer WagmanDepartment of Community Health Sciences, UCLA Fielding School of Public Health, 650 Charles E. Young Drive South, Los Angeles, CA, 90095, USA.
Tulane University · USUCLA Health · USJacobs (United States) · USLouisiana State University Health Sciences Center New Orleans · USPartners in Care Foundation · US

Funding

CDC HHS U380T000199-05-00
6 · The paper itself

Abstract

backgroundCongenital syphilis is preventable through timely access to prenatal care, syphilis screening and treatment of pregnant women diagnosed as infected. In 2018, California had the second highest number of congenital syphilis cases in the United States (U.S.), a nearly twofold increase in cases since 2014. This study assessed gaps in preventing congenital syphilis in the high morbidity region of Kern County, California.

methodsBetween May 2018 and January 2019, we conducted five focus group discussions with pregnant/postpartum women and ten semi-structured interviews with prenatal care providers in Kern County. Focus group and interview data were recorded, transcribed, and analyzed to identify emergent themes pertaining to facilitators and barriers at each step (prenatal care, syphilis screening and treatment) in the congenital syphilis prevention cascade.

resultsGaps in congenital syphilis prevention discussed in focus group discussions with pregnant/postpartum women were related to limited prenatal care access, social-, economic-, and cultural-barriers, and substance use and co-occurring intimate partner/domestic violence. The gaps identified from interviews with prenatal care providers included social economic vulnerabilities of pregnant women and stigma and shame around the vulnerabilities, distrust in medical system, prenatal substance use, limited prenatal substance use disorder treatment facilities, and inadequate provider training on context-specific congenital syphilis management strategies. Gaps in partner notification, screening and treatment for syphilis were brought up by pregnant/postpartum women and prenatal care providers.

conclusionsCongenital syphilis continues to increase in Kern County and throughout the U.S. In high syphilis morbidity areas, comprehensive and tailored public health approaches addressing setting-specific gaps in prenatal screening and treatment are needed.

Indexed as

Pregnancy Complications, InfectiousSyphilisSyphilis, CongenitalFemaleHumansPregnancyPregnant PeoplePrenatal CareUnited StatesCongenital syphilisPrenatal careQualitative methodsSexually transmitted infectionSocial determinants of healthSyphilis screening

Identifiers

PMID35123425
PMCPMC8818245
OpenAlexW4225361951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.