Evidence map›Paper›PMID 35123377›Full record

ArticleDiagnostic microbiology and infectious disease2022

SARS-CoV-2 screening in patients in need of urgent inpatient treatment in the Emergency Department (ED) by digitally integrated point-of-care PCR: a clinical cohort study.

Martin Möckel, Myrto Bolanaki, Jörg Hofmann, Angela Stein, Jennifer Hitzek, Fabian Holert, Antje Fischer-Rosinský, Anna Slagman

Open access · greenAbstract read
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Effects of Different SARS-CoV-2 Testing Strategies in the Emergency Department on Length of Stay and Clinical Outcomes: A Randomised Controlled Trial.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Martin MöckelDepartment of Emergency and Acute Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany. Electronic address: martin.moeckel@charite.de.
Myrto BolanakiDepartment of Emergency and Acute Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Jörg HofmannInstitute of Virology, Charité - Universitätsmedizin Berlin and Labor Berlin - Charité Vivantes GmbH, Berlin, Germany.
Angela SteinInstitute of Virology, Charité - Universitätsmedizin Berlin and Labor Berlin - Charité Vivantes GmbH, Berlin, Germany.
Jennifer HitzekDepartment of Emergency and Acute Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Fabian HolertDepartment of Emergency and Acute Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Antje Fischer-RosinskýDepartment of Emergency and Acute Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Anna SlagmanDepartment of Emergency and Acute Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients in need of urgent inpatient treatment were recruited prospectively. A rapid point of care polymerase chain reaction test (POC-PCR; Liat®) for SARS-CoV2 was conducted in the Emergency Department (ED) and a second PCR-test from the same swab was ordered in the central laboratory (PCR). POC-PCR analyzers were digitally integrated in the laboratory information system. Overall, 160 ED patients were included. A valid POC-PCR-test result was available in 96.3% (n = 154) of patients. N = 16 patients tested positive for Severe Acute Respiratory Syndrome-Corona Virus 2 (10.0%). The POC PCR test results were available within 102 minutes (median, interquartile range: 56-211), which was significantly earlier compared to the central laboratory PCR (811 minutes; interquartile range: 533-1289, P < 0.001). The diagnostic accuracy of the POC-PCR test was 100%. The implementation and digital laboratory information system integration was successfully done. Staff satisfaction with the POC process was high. The POC-PCR testing in the ED is feasible and shows a very high diagnostic performance. Trial registration: DRKS00019207.

Indexed as

COVID-19Point-of-Care SystemsCohort StudiesEmergency Service, HospitalHumansInpatientsPolymerase Chain ReactionRNA, ViralSARS-CoV-2RNA, ViralCritical interventionsDigital integrationEmergency DepartmentPOC PCRSARS-CoV-2

Identifiers

PMID35123377
PMCPMC8761116
OpenAlexW4205393455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.