ArticleDrug and alcohol dependence2022
Short communication: Relationship between social determinants and opioid use disorder treatment outcomes by gender.
Article in Drug and alcohol dependence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 14 citations in OpenAlex.
- Treatment Initiation, Substance Use Trajectories, and the Social Determinants of Health in Persons Living With HIV Seeking Medication for Opioid Use Disorder.Substance abuse · 2023Trial
- Differential associations between social determinants of health and the initiation of medications for opioid use disorder across care settings.npj health systems · 2026Article
- Non-death losses experienced by Black adults who use opioids.Journal of loss & trauma · 2026Article
- Real-world effectiveness of medication-assisted treatment and psychotherapy for opioid use disorder: a national multi-health care organization analysis.Frontiers in psychiatry · 2026Article
- Sex differences in the impact of social determinants of health on substance use disorder treatment outcomes.Biology of sex differences · 2025Article
- Extended-release Injectable Buprenorphine Initiation in the Emergency Department.The western journal of emergency medicine · 2025Article
- Effects of E-cigarettes on Combustible Cigarette Smoking Among Adults With Opioid Use Disorder on Buprenorphine: Single Arm ERASER Pilot Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Lessons from the National institutes of health innovation corps program: defining barriers to developing and commercializing novel solutions for persons with opioid use disorder.Addiction science & clinical practice · 2025Article
- Fostering Safety, Support, and Hope: A Qualitative Study of Multistakeholder Perspectives on Designing Health Care Services for Women Who Use Drugs in Seattle, Washington, 2023.Women's health reports (New Rochelle, N.Y.) · 2025Article
- Commentary on Cochran et al.: Meeting people where they are in addictions research.Addiction (Abingdon, England) · 2024Article
- Development and validation of a community-level social determinants of health index for drug overdose deaths in the HEALing Communities Study.Journal of substance use and addiction treatment · 2024Article
- Co-occurring psychiatric disorders and disparities in buprenorphine utilization in opioid use disorder: An analysis of insurance claims.Drug and alcohol dependence reports · 2023Article
- Postpartum medication for opioid use disorder outcomes associated with prenatal treatment and neighborhood-level social determinants.American journal of obstetrics & gynecology MFM · 2023Article
- Article
- Housing instability and economic insecurity across the continuum of active substance use, treatment, and recovery among women involved in the criminal legal system.Women's health (London, England)Article
- Association of Socioeconomic and Psychiatric Factors with Postoperative Opioid Use Disorder: A Retrospective Cohort Analysis.Substance use : research and treatmentArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundSocial determinants of health (SDoH) influence health outcomes differentially across gender. Gender differences in SDoH have been identified at baseline in opioid use disorder (OUD) treatment studies, but less is known about how SDoH and gender intersect with OUD treatment trajectories. This study aims to identify social correlates of OUD treatment outcomes from five key areas of social determinants separately for men and women receiving buprenorphine for OUD.
methodsThis is a secondary data analysis of a cross-sectional survey with medical record review conducted with patients recruited from an office based opioid treatment clinic. Participants completed surveys between July-September 2019. A 6-month prospective medical record review was conducted to determine treatment retention, substance use recurrence, and buprenorphine continuation. Chi square, T-tests, and Mann Whitney U tested differences in social factors and OUD outcomes by gender. Gender-stratified multivariable logistic and negative binomial regressions assessed predictors of OUD outcomes.
resultsAmong study participants (n = 142), women were significantly younger (p < 0.001), more likely to live in a safe neighborhood (p = 0.046), and less likely to be employed (p = 0.005) or have substance use recurrence during the study period (p = 0.033) than men. For women, employment (AOR=0.19, p = 0.031) and education (AOR=0.08, p = 0.040) were negatively associated with treatment retention. For men, no social factors were associated with OUD outcomes.
conclusionsSDoH may impact OUD treatment outcomes differently by gender. Addressing MOUD stigma and implementing patient-centered care strategies may facilitate OUD treatment continuation among employed women in recovery. Gender-related social factors should be considered in OUD treatment research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.