Evidence map›Paper›PMID 35123311›Full record

ArticleTheriogenology2022

Limitations in use of ovarian reserve biomarkers to predict the superovulation response in small ovarian reserve heifers.

Kaitlin R Karl, Janet L H Ireland, Zaramasina L Clark, Robert J Tempelman, Keith E Latham, James J Ireland

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theriogenology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kaitlin R KarlMolecular Reproductive Endocrinology Laboratory, Department of Animal Science, Michigan State University, East Lansing, MI, 48824, USA.
Janet L H IrelandMolecular Reproductive Endocrinology Laboratory, Department of Animal Science, Michigan State University, East Lansing, MI, 48824, USA.
Zaramasina L ClarkMolecular Reproductive Endocrinology Laboratory, Department of Animal Science, Michigan State University, East Lansing, MI, 48824, USA.
Robert J TempelmanMolecular Reproductive Endocrinology Laboratory, Department of Animal Science, Michigan State University, East Lansing, MI, 48824, USA.
Keith E LathamMolecular Reproductive Endocrinology Laboratory, Department of Animal Science, Michigan State University, East Lansing, MI, 48824, USA.
James J IrelandMolecular Reproductive Endocrinology Laboratory, Department of Animal Science, Michigan State University, East Lansing, MI, 48824, USA. Electronic address: ireland@msu.edu.
Michigan State University · US

Funding

Reproductive and Developmental Sciences Training Program - T32T32HD087166 · NICHD · MICHIGAN STATE UNIVERSITY · PI Ronald L Chandler, Keith E Latham · 2016 to 2026
$2.5M
NICHD NIH HHS T32 HD087166
6 · The paper itself

Abstract

High FSH doses during superovulation of heifers with a small ovarian reserve increase the number of dysfunctional ovulatory-size follicles that do not ovulate in response to human chorionic gonadotropin (hCG). Thus, anti-Müllerian hormone (AMH) and antral follicle count (AFC), two well-established biomarkers of responsiveness of individuals to superovulation, are hypothesized to be positively linked to number of dysfunctional ovulatory-size follicles developing in response to superovulation with high FSH doses. To test this hypothesis, heifers with a small ovarian reserve were stimulated beginning on Day 1 of the estrous cycle with twice daily treatments for 4 days with each of four Folltropin-V (FSH) doses (35 IU, 70 IU (industry standard), 140 IU, or 210 IU) followed by prostaglandin F

Indexed as

Ovarian ReserveSuperovulationAnimalsAnti-Mullerian HormoneBiomarkersCattleFemaleFollicle Stimulating HormoneOvarian FollicleAnti-Mullerian HormoneBiomarkersFollicle Stimulating Hormoneanti-Mϋllerian hormoneBiomarkersBovineDysfunctional ovulatory-size folliclesSmall ovarian reserveSuperovulation

Identifiers

PMID35123311
PMCPMC8863639
OpenAlexW4210475502

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.