ReviewLancet (London, England)2022
Responding to the opioid crisis in North America and beyond: recommendations of the Stanford-Lancet Commission.
Registry-linked trialAbstract readReview
In one paragraph
Review in Lancet (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02464410 (Primary Care Intervention to Reduce Prescription Opioid Overdoses), which is not on this map. Cited by 240 papers, 6 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
240citing papers in PubMed, 6 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Primary Care Intervention to Reduce Prescription Opioid Overdoses
Who cites it
240 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Pharmacological treatment strategies to manage precipitated withdrawal following the administration of buprenorphine in opioid use disorder: A systematic review.Addiction (Abingdon, England) · 2026Pooled it
- Shedding light on pain management: a translational systematic review of light therapy for the treatment of chronic pain.EBioMedicine · 2026Pooled it
- Effect of intrathecal morphine compared with truncal nerve blocks on postoperative analgesia in adults : A meta-analysis of randomized controlled trials.Die Anaesthesiologie · 2026Pooled it
- Effect of Bilateral Superficial Cervical Plexus Block on Postoperative Pain in Thyroid and Parathyroid Surgery: A Systemic Review and Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2025Pooled it
- A multi-ancestry genetic study of pain intensity in 598,339 veterans.Nature medicine · 2024Pooled it
- Pooled it
- Reduced opioids after total joint replacement surgery (REPAIRS): a pilot randomized controlled trial.Journal of orthopaedic surgery and research · 2025Trial
- Best Practice Alerts Informed by Inpatient Opioid Intake to Reduce Opioid Prescribing after Surgery (PRIOR): A Cluster Randomized Multiple Crossover Trial.Anesthesiology · 2023Trial
- Low early post-operative pain is a strong predictor of favorable outcomes after rotator cuff repair.JSES international · 2026Article
- Real-world comparative effects of slow-release oral morphine vs. methadone on healthcare use for opioid use disorder: A population-based target trial emulation.Addiction (Abingdon, England) · 2026Article
- Persistent Opioid Exposure in Older Adults with Rheumatic Disease: National Patterns, Disparities, and Cross-Specialty Prescribing.The Journal of rheumatology · 2026Article
- Global burden of self-harm attributable to drug use from 1990 to 2021: evidence from the global burden of disease study.European archives of psychiatry and clinical neuroscience · 2026Article
- Article
- Superficial parasternal intercostal plane block with ropivacaine versus placebo for opioid exposure after cardiac surgery (EPOCH CardioLink-10): a multicentre, double-blind, randomised trial.Lancet regional health. Americas · 2026Article
- Experiences of non-prescribed opioid use during opioid agonist therapy: an interpretative phenomenological analysis.Addiction science & clinical practice · 2026Article
- The Rise of Synthetic Drugs: New Challenges for Global Drug Control.China CDC weekly · 2026Article
- The Emerging Burden of Opioid Poisoning in Brazil, 2019-2025: A Nationwide Epidemiological and Toxicovigilance Analysis.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Ion Channels and Neurological Disease-2nd Edition.Life (Basel, Switzerland) · 2026Article
- Invisible pain: Sex/gender differences in pain-related stigma.Acta psychologica · 2026Article
- Reframing Buprenorphine as a Pharmacologic Modifier of Opioid-Induced Respiratory Depression in the Fentanyl Era.Pharmaceuticals (Basel, Switzerland) · 2026Article
180 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
17 authors.
Keith HumphreysDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA; Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA. Electronic address: knh@stanford.edu.
Chelsea L ShoverDivision of General Internal Medicine and Health Services Research, University of California Los Angeles David Geffen School of Medicine, Los Angeles, CA, USA.
Christina M AndrewsDepartment of Health Services Policy and Management, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Amy S B BohnertDepartment of Psychiatry and Department of Anesthesiology, University of Michigan Health System, Ann Arbor, MI, USA; Veterans Affairs Center for Clinical Management Research, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Margaret L BrandeauDepartment of Management Science and Engineering, Huang Engineering Center, Stanford University, Stanford, CA USA.
Jonathan P CaulkinsHeinz College, Carnegie Mellon University, Pittsburgh, PA, USA.
Jonathan H ChenStanford Center for Biomedical Informatics Research, Stanford University School of Medicine, Stanford, CA, USA; Division of Hospital Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Mariano-Florentino CuéllarStanford Law School, Stanford, CA, USA.
Yasmin L HurdAddiction Institute, Icahn School of Medicine, New York, NY, USA.
David N JuurlinkSunnybrook Health Sciences Centre, Toronto, ON, Canada; Department of Medicine, University of Toronto, Toronto, ON, Canada.
Howard K KohDepartment of Health Policy and Management, Harvard T H Chan School of Public Health, Boston, MA, USA.
Erin E KrebsDepartment of Medicine, University of Minnesota, Minneapolis, MN, USA; Center for Care Delivery and Outcomes Research, Veterans Affairs Minneapolis Health Care System, Minneapolis, MN, USA.
Anna LembkeDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Sean C MackeyDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Lisa Larrimore OuelletteStanford Law School, Stanford, CA, USA.
Brian SuffolettoDepartment of Emergency Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Christine TimkoDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA; Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA.
Funding
Technical Assistance CoreU2CDA050097 · NIDA · GEORGE MASON UNIVERSITY · PI Todd David Molfenter, Jessica Hulsey Nickel · 2019 to 2026
$37.0MTRANSGENIC COREP01DA008227 · NIDA · YALE UNIVERSITY · PI NESTLER, ERIC J. · 1993 to 2018
$28.1MThe Center for Enhancing Triage and Utilization for Depression and Emergent Suicidality (ETUDES) in Pediatric Primary CareP50MH115838 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI David A. Brent · 2018 to 2026
$25.5MWestern States Node of the National Drug Abuse Treatment Clinical Trials Network (TMS for CUD) UG1DA015815 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Keith N. Humphreys, Philip Todd Korthuis · 2015 to 2026
$24.6MCannabidiol in the treatment of opioid use disorderUH3DA050323 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HURD, YASMIN L. · 2024 to 2024
$10.3MCannabidiol in the treatment of opioid use disorderUG3DA050323 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HURD, YASMIN L. · 2019 to 2019
$7.5MPrognostic biomarkers for high-impact chronic pain: Development and validationR61NS118651 · NINDS · STANFORD UNIVERSITY · PI MACKEY, SEAN C · 2020 to 2020
$7.3MInterdisciplinary Research Training in Pain and Substance Use DisordersT32DA035165 · NIDA · STANFORD UNIVERSITY · PI SEAN C MACKEY · 2013 to 2026
$7.2MThe Opioid mesolimbic system in heroin abuseR01DA015446 · NIDA · KAROLINSKA INSTITUTE · PI HURD, YASMIN L. · 2002 to 2018
$7.1MMaking Better Decisions: Policy Modeling for AIDS and Drug AbuseR37DA015612 · NIDA · STANFORD UNIVERSITY · PI DOUGLAS K OWENS · 2019 to 2026
$6.3MNeurodevelopmental Effects of Cannabis and its Epigenetic RegulationR01DA030359 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HURD, YASMIN L. · 2011 to 2020
$5.5MStanford Medicine Center for Longevity and Healthy Aging Research Education CoreP30AG059307 · NIA · STANFORD UNIVERSITY · PI ZOU, JAMES · 2018 to 2025
$4.9MHSRD VA I01 HX000911HSRD VA I01 HX001288HSRD VA I01 HX001752HSRD VA I01 HX002714HSRD VA I01 HX002737HSRD VA I01 HX003063NCCIH NIH HHS R01 AT008387NCCIH NIH HHS R01 AT008561NCCIH NIH HHS UG3 AT009761NCCIH NIH HHS UG3 AT009765NCIPC CDC HHS U01 CE002780NIAAA NIH HHS K23 AA023284NIAAA NIH HHS R01 AA023650NIAAA NIH HHS R01 AA024136NIA NIH HHS P30 AG059307NICHD NIH HHS R03 HD094577NIDA NIH HHS K01 DA041628NIDA NIH HHS K01 DA050771NIDA NIH HHS P01 DA008227NIDA NIH HHS R01 DA015446NIDA NIH HHS R01 DA030359NIDA NIH HHS R01 DA034634NIDA NIH HHS R01 DA035484NIDA NIH HHS R01 DA037317NIDA NIH HHS R01 DA043247NIDA NIH HHS R01 DA045027NIDA NIH HHS R01 DA045705NIDA NIH HHS R01 DA048613NIDA NIH HHS R01 DA049776NIDA NIH HHS R21 DA043181NIDA NIH HHS R37 DA015612NIDA NIH HHS R56 DA015446NIDA NIH HHS T32 DA035165NIDA NIH HHS U2C DA050097NIDA NIH HHS UG1 DA015815NIDA NIH HHS UG3 DA050323NIDA NIH HHS UH3 DA050323NIDDK NIH HHS U01 DK123816NIMH NIH HHS P50 MH115838NINDS NIH HHS R01 NS109450NINDS NIH HHS R61 NS118651NLM NIH HHS R56 LM013365
Abstract
PubMed holds no abstract for this paper.
Indexed as
Opioid EpidemicAnalgesics, OpioidCOVID-19FemaleGlobal HealthHealth PolicyHumansMaleNorth AmericaOpioid-Related DisordersPainPractice Guidelines as TopicAnalgesics, Opioid
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
NCT02464410ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.