ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2022
Enhanced production of cordycepic acid from Cordyceps cicadae isolated from a wild environment.
Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Molecular Mechanisms of Temperature-Regulated Cordycepin Biosynthesis inJournal of fungi (Basel, Switzerland) · 2026Article
- TheIMA fungus · 2026Article
- Filtration effect ofMicrobiology spectrum · 2024Article
- Exploiting the roles of nitrogen sources for HEA increment inFrontiers in microbiology · 2024Article
- Genomic Comparison of Two Species ofJournal of fungi (Basel, Switzerland) · 2023Article
- The Health and Clinical Benefits of Medicinal Fungi.Advances in biochemical engineering/biotechnology · 2023Article
- Exploration of the potential utilization value inScience progressArticle
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Authors and funding
6 authors.
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Abstract
Cordyceps acid is an active component of Cordyceps cicadae and has a variety of medicinal uses, including anti-tumor effects, the prevention of cerebral hemorrhaging and myocardial infarction, and the inhibition of a wide range of bacteria. The objectives of this study were to identify C. cicadae fungi and optimize the culture conditions to obtain a high yield of cordycepic acid. First, a wild C. cicadae was identified by morphological observation and rDNA sequence analysis. Secondly, the optimal fermentation conditions were determined using a single-factor method, a Plackett-Burman design, and a Box-Behnken response surface. Finally, using the yield of fruit bodies and the content of cordyceps acid as indices, combined with a single-factor experiment and a response surface design, the best combination of conditions for cultivation was determined. The results showed that the best combination was as follows: sucrose 2%, tryptone 2%, KH
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