Evidence map›Paper›PMID 35122630›Full record

ReviewJournal of endocrinological investigation2022

Which physical activity in patients affected by hypoparathyroidism? A review of the literature and practical recommendations.

V Bonavolontà, L Cianferotti, G Iolascon, A Moretti, M L Brandi, F Fischetti, A Lenzi, C Baldari, S Migliaccio

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of endocrinological investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

V BonavolontàDepartment of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari "Aldo Moro", Bari, Italy.
L CianferottiBone Metabolic Diseases Unit, Department of Experimental and Clinical Biomedical Sciences, University of Firenze, Firenze, Italy.
G IolasconDepartment of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Napoli, Italy.
A MorettiDepartment of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Napoli, Italy.
M L BrandiFondazione Firmo, Firenze, Italy.
F FischettiDepartment of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari "Aldo Moro", Bari, Italy.
A LenziDepartment of Experimental Medicine, Sapienza University of Roma, Roma, Italy.
C BaldariDepartment of Theoretical and Applied Sciences, eCampus University, Roma, Italy.
S MigliaccioDepartment of Movement, Human and Health Sciences, University Foro Italico of Roma, Piazza Lauro De Bosis 6, 00195, Roma, Italy. silvia.migliaccio@uniroma4.it.ORCID http://orcid.org/0000-0002-4563-6630
University of Bari Aldo Moro · ITUniversity of Campania "Luigi Vanvitelli" · ITForo Italico University of Rome · ITSapienza University of Rome · ITUniversità degli Studi eCampus · ITUniversity of Florence · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca PRIN2017HBHA98_004Regione Puglia 1273/2016Takeda Pharmaceutical Company IIR-ITA-001336
6 · The paper itself

Abstract

backgroundHypoparathyroidism (HypoP) is a rare endocrine condition characterized by hypocalcaemia and hyperphosphatemia, as a consequence of absent or improperly low parathyroid hormone (PTH) levels. Patients affected by HypoP have a clinical condition often characterized by paresthesias and muscle spasms, as well as long-term consequences as nephrolithiasis, extraskeletal calcification, and fractures. In the literature, likely due to these symptoms, few data exist regarding the appropriate physical activity (PA) in subjects suffering from HypoP. PURPOSE: This review evaluates the literature on exercise-based approaches to the management of individuals affected by HypoP and evaluates: (1) the effects of physical exercise on muscle cramps and other clinical symptoms; (2) the effects of exercise on PTH and calcium level; (3) the most suitable clinical exercise testing; and (4) the most suitable exercise combination. METHODS AND

resultsA systematic search was conducted using the databases MEDLINE, Google Scholar using "hypoparathyroidism AND Physical Activity", "Training AND hypoparathyroidism", "Exercise AND muscle cramps", "Exercise AND Fatigue" as keywords. In addition, references list from the included articles were searched and cross-checked to identify any further potentially eligible studies. A total of 50 manuscripts were found among which 39 manuscripts were selected. A few clinical studies have been performed in HypoP patients to evaluate PA training protocols.

conclusionAlthough further research is needed to draw solid conclusions regarding best PA protocols in subjects affected by HypoP, a PA protocol has been proposed within the manuscript to encourage patients to attempt exercise to improve their clinical conditions and their quality of life.

Indexed as

HypoparathyroidismParathyroid HormoneExerciseHumansMuscle CrampQuality of LifeParathyroid HormoneFatigueHypoparathyroidismMuscle crampsParathyroid hormonePhysical activity

Identifiers

PMID35122630
OpenAlexW4210808975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.