Evidence map›Paper›PMID 35122570›Full record

ArticleInflammation2022

LncRNA HCP5 Participates in the Tregs Functions in Allergic Rhinitis and Drives Airway Mucosal Inflammatory Response in the Nasal Epithelial Cells.

Chen Yang, Chengfang Shangguan, Changing Cai, Jing Xu, Xiaohua Qian

Open access · hybridAbstract read
In one paragraph

Article in Inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. Astaxanthin ameliorates allergic rhinitisCentral-European journal of immunology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chen Yang *Department of Otolaryngology & Head and Neck Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, 197 Ruijiner Road, Shanghai, 200025, China.
Chengfang Shangguan *Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, Shanghai, 200025, China.
Changing CaiDepartment of Otolaryngology & Head and Neck Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, 197 Ruijiner Road, Shanghai, 200025, China. drcaichangping@163.com.ORCID http://orcid.org/0000-0002-4566-5140
Jing XuDepartment of Otolaryngology & Head and Neck Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, 197 Ruijiner Road, Shanghai, 200025, China.
Xiaohua QianSchool of Biomedical Engineering, Shanghai Jiao Tong University, Xuhui District, 1954 Huashan Road, Shanghai, 200240, China.
Shanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergic rhinitis (AR) is an allergic disease characterized as (immunoglobulin, IgE)-mediated type I hypersensitivity disorder. Regulatory T cells (Tregs) play a crucial role in AR. In the present study, we aimed to investigate the mechanism of how Tregs are regulated by long noncoding RNA HCP5 and the regulatory role of HCP5 in IL-13-induced inflammatory response in nasal epithelial cells (NECs) from AR patients. Peripheral blood mononuclear cells (PBMCs) and NECs were obtained from collected blood samples and nasal epithelial tissues. CD4

Indexed as

MicroRNAsRhinitis, AllergicEpithelial CellsGranulocyte-Macrophage Colony-Stimulating FactorHumansInterleukin-13Leukocytes, MononuclearNasal MucosaRNA, Long NoncodingGranulocyte-Macrophage Colony-Stimulating FactorHCP5 long noncoding RNA, humanInterleukin-13MicroRNAsRNA, Long Noncodingallergic rhinitisATXN2Llong noncoding RNA HCP5miRNA-16NECs.regulatory T cells

Identifiers

PMID35122570
PMCPMC9095562
OpenAlexW4210377410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.