Evidence map›Paper›PMID 35122523›Full record

ArticleArchives of osteoporosis2022

Does hip structural analysis confer additional benefit to routine BMD assessment in postmenopausal women with hip fracture? A study from a tertiary center in southern India.

Johns T Johnson, Kripa Elizabeth Cherian, Nitin Kapoor, Felix K Jebasingh, Hesarghatta Shyamsunder Asha, Thomas Mathai, Manasseh Nithyananth, Anil Thomas Oommen, Alfred Job Daniel, Nihal Thomas and 1 more

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Article in Archives of osteoporosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Quantitating Age-Related BMD Textural Variation from DXA Region-Free-Analysis: A Study of Hip Fracture Prediction in Three Cohorts.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Johns T JohnsonDepartment of Endocrinology, Christian Medical College, Vellore, India, 632004.
Kripa Elizabeth CherianDepartment of Endocrinology, Christian Medical College, Vellore, India, 632004. kripaec@gmail.com.
Nitin KapoorDepartment of Endocrinology, Christian Medical College, Vellore, India, 632004.
Felix K JebasinghDepartment of Endocrinology, Christian Medical College, Vellore, India, 632004.
Hesarghatta Shyamsunder AshaDepartment of Endocrinology, Christian Medical College, Vellore, India, 632004.
Thomas MathaiDepartment of Orthopedics, Christian Medical College, Tamil Nadu, Vellore, India, 632004.
Manasseh NithyananthDepartment of Orthopedics, Christian Medical College, Tamil Nadu, Vellore, India, 632004.
Anil Thomas OommenDepartment of Orthopedics, Christian Medical College, Tamil Nadu, Vellore, India, 632004.
Alfred Job DanielDepartment of Orthopedics, Christian Medical College, Tamil Nadu, Vellore, India, 632004.
Nihal ThomasDepartment of Endocrinology, Christian Medical College, Vellore, India, 632004.
Thomas Vizhalil PaulDepartment of Endocrinology, Christian Medical College, Vellore, India, 632004.
Christian Medical College & Hospital · INChristian Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study from southern India showed that proximal hip geometry was significantly impaired in postmenopausal women with femoral neck fracture. The trabecular bone score (TBS), which is reflective of bone microarchitecture, was also significantly impaired in patients with fracture.

introductionThere is limited information with regard to comprehensive bone health in Indian postmenopausal women with neck of femur fracture. We studied the bone mineral density (BMD), trabecular bone score (TBS), proximal hip geometry, and bone mineral biochemistry in postmenopausal women with and without femoral neck fractures.

methodsThis was a cross-sectional study conducted at a tertiary care center in South India. BMD, TBS, and hip structural analysis (HSA) were assessed using a dual-energy X-ray absorptiometry (DXA) scanner. Bone mineral biochemical profiles were also studied.

resultsA total of 90 postmenopausal women with acute femoral neck fracture with mean (SD) age of 63.2 (6.1) years and 90 age-matched controls were included. The prevalence of osteoporosis was higher among cases as compared to controls (83.3% vs 47.8%; P < 0.001). Degraded bone microarchitecture (TBS value < 1.200) was more frequent among women with hip fracture as compared to controls (46.7% vs 31.1%; P = 0.032). Cross-sectional moment of inertia (CSMI) was significantly lower at the narrow neck (NN) and inter-trochanteric (IT) region in cases (P < 0.05) and buckling ratio (BR) was significantly higher at all three sites in postmenopausal women with femoral neck fracture as compared controls. Multivariate logistic regression analysis showed that femoral neck osteoporosis, low CSMI at NN and high BR at NN and femoral shaft emerged as factors significantly associated with femoral neck fractures.

conclusionThis study highlights that impaired parameters of proximal hip geometry and a low trabecular bone score may be significantly associated with femoral neck fractures in postmenopausal women.

Indexed as

Hip FracturesOsteoporosis, PostmenopausalAbsorptiometry, PhotonBone DensityCross-Sectional StudiesFemaleFemur NeckHumansMiddle AgedPostmenopauseHip structural analysisIndiaNeck of femur fracturePostmenopausal osteoporosisProximal hip geometryTrabecular bone score

Identifiers

PMID35122523
OpenAlexW4210403487

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.