ArticleEuropean journal of nutrition2022
Dietary total antioxidant capacity and mortality outcomes: the Singapore Chinese Health Study.
Article in European journal of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Association of the Composite Dietary Antioxidant Index with All-Cause, Cancer, and Cardiovascular Mortality: A Prospective Cohort Study.Food science & nutrition · 2026Article
- Intake of dietary carotenoids and flavonoids at midlife and risk of physical frailty at late life: the Singapore Chinese Health Study.Nutrition journal · 2025Article
- Consumption of ultra-processed foods and risk of all-cause and cause-specific mortality: the Singapore Chinese health study.Nutrition journal · 2025Article
- Joint and independent associations of dietary antioxidant intakes with all-cause and cardiovascular mortality among patients with hypertension: a population-based cohort study.Nutrition journal · 2025Article
- Reduced composite dietary antioxidant index increases the risk of Parkinson's disease and all-cause mortality in Parkinson's disease patients: evidence from the NHANES database.Frontiers in aging neuroscience · 2025Article
- Association between dietary antioxidant intake and overweight/obesity risk among children and adolescents: a cross-sectional analysis from NHANES 2011-2016.Frontiers in nutrition · 2025Article
- Associations of dietary inflammation index and composite dietary antioxidant index with all-cause mortality in COPD patients.Frontiers in nutrition · 2025Article
- Composite dietary antioxidant index, chronic respiratory disease, and all-cause mortality: National Health and Nutrition Examination Survey, 2003-2018.European journal of nutrition · 2024Article
- Article
- Association of dietary antioxidant intake with depression risk and all-cause mortality in people with prediabetes.Scientific reports · 2024Article
- Dietary antioxidant and inflammatory potential in asthmatic patients and its association with all-cause mortality.Nutrition journal · 2024Article
- Scientific opinion on the tolerable upper intake level for vitamin E.EFSA journal. European Food Safety Authority · 2024Article
- Dietary inflammatory index, dietary total antioxidant capacity, and frailty among older Chinese adults.The journal of nutrition, health & aging · 2024Article
- Composite dietary antioxidant index and sleep health: a new insight from cross-sectional study.BMC public health · 2024Article
- Exploring the application of dietary antioxidant index for disease risk assessment: a comprehensive review.Frontiers in nutrition · 2024Review
- Adherence to a Planetary Health Diet, Environmental Impacts, and Mortality in Chinese Adults.JAMA network open · 2023Article
- Meal timing of dietary total antioxidant capacity and its association with all-cause, CVD and cancer mortality: the US national health and nutrition examination survey, 1999-2018.The international journal of behavioral nutrition and physical activity · 2023Article
- Dietary Total Antioxidant Capacity, a Diet Quality Index Predicting Mortality Risk in US Adults: Evidence from the NIH-AARP Diet and Health Study.Antioxidants (Basel, Switzerland) · 2023Article
- Association of dietary total antioxidant capacity and its distribution across three meals with all-cause, cancer, and non-cancer mortality among cancer survivors: the US National Health and Nutrition Examination Survey, 1999-2018.Frontiers in nutrition · 2023Article
- Association between dietary total antioxidant capacity and semen quality among men attending an infertility clinic: a cross-sectional study.Human reproduction open · 2023Article
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Abstract
purposeTo evaluate the relations of dietary total antioxidant capacity (DTAC) with mortality outcomes in a Chinese population.
methodsThe study included 62,063 participants from the Singapore Chinese Health Study. The participants were 45-74 years at baseline (1993-1998) when dietary data were collected with a validated 165-item food frequency questionnaire. The DTAC was derived using two widely adopted scores of integrated dietary consumption of antioxidant nutrients, i.e., the Comprehensive Dietary Antioxidant Index (CDAI) and Vitamin C Equivalent Antioxidant Capacity (VCEAC). We used Cox proportional hazard model to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) for the associations with adjustment for potential confounders.
resultsDuring 1,212,318 person-years of follow-up, 23,397 deaths [cardiovascular diseases (CVD): 7523; respiratory diseases: 4696; and cancer: 7713] occurred. In multivariable models, the HR (95% CI) comparing participants in the highest vs. lowest quartile of CDAI was 0.85 (0.82, 0.88) for all-cause mortality, 0.82 (0.76, 0.88) for CVD mortality, 0.76 (0.70, 0.83) for respiratory disease mortality (all P-trend < 0.001), and 0.94 (0.88, 1.00) for cancer mortality (P-trend = 0.16). Similar associations were found with the VCEAC index. Higher intakes of the DTAC components, i.e., vitamin C, vitamin E, carotenoids, and flavonoids, were all associated with lower mortality risk.
conclusionDiet with a higher antioxidant capacity in midlife was associated with a lower risk of all-cause, cardiovascular and respiratory disease mortality in the Singapore Chinese population, supporting the public health recommendation of consuming more plant-based foods that are rich in antioxidant nutrients.
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