Evidence map›Paper›PMID 35122290›Full record

ArticleArtificial organs2022

Similarities in extracorporeal membrane oxygenation management across intensive care unit types in the United States: An analysis of the Extracorporeal Life Support Organization Registry.

Clark G Owyang, Claire Donnat, Daniel Brodie, Hayley B Gershengorn, May Hua, Nida Qadir, Joseph E Tonna

Abstract read
In one paragraph

Article in Artificial organs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Clark G OwyangDivision of Pulmonary and Critical Care Medicine, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, New York, USA.ORCID https://orcid.org/0000-0001-9435-2944
Claire DonnatDepartment of Statistics, Stanford University, Stanford, California, USA.
Daniel BrodieDepartment of Medicine, Columbia University College of Physicians & Surgeons/NewYork-Presbyterian Hospital, New York, New York, USA.
Hayley B GershengornDivision of Pulmonary, Critical Care, and Sleep Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA.
May HuaDepartment of Anesthesiology, Columbia University College of Physicians & Surgeons, New York, New York, USA.
Nida QadirDivision of Pulmonary and Critical Care Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Joseph E TonnaDivision of Cardiothoracic Surgery, Department of Surgery, University of Utah Health, Salt Lake City, Utah, USA.

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
University of Utah Center for Clinical and Translational ScienceUL1TR001067 · NCATS · UNIVERSITY OF UTAH · PI DERE, WILLARD H., HESS, RACHEL · 2013 to 2017
$19.8M
UNIVERSITY OF UTAH CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE-UL1: BPCAUL1RR025764 · NCRR · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2008 to 2011
$19.4M
University of Utah Center for Clinical and Translational Science-UL1UL1TR000105 · NCATS · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2012 to 2013
$5.1M
Optimizing Selection and Management of Cardiac Arrest Patients Treated with ECMOK23HL141596 · NHLBI · UNIVERSITY OF UTAH · PI TONNA, JOSEPH EDWARD · 2018 to 2022
$945k
Determinants of Critical Care Intensity for Hospitalized Older Adults: the Effect of Hospital-based Palliative Care ServicesK08AG051184 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HUA, MAY · 2015 to 2019
$863k
NCATS NIH HHS UL1 TR000105NCATS NIH HHS UL1 TR001067NCATS NIH HHS UL1 TR002538NCATS NIH HHS UL1TR002538NCRR NIH HHS UL1 RR025764NCRR NIH HHS UL1TR002538NHLBI NIH HHS K23 HL141596NIA NIH HHS K08 AG051184NIA NIH HHS K08AG051184
6 · The paper itself

Abstract

backgroundExtracorporeal membrane oxygenation (ECMO) use in the United States occurs often in cardiothoracic ICUs (CTICU). It is unknown how it varies across ICU types.

methodsWe identified 10 893 ECMO runs from the Extracorporeal Life Support Organization (ELSO) Registry across 2018 and 2019. Primary outcome was ECMO case volume by ICU type (CTICU vs. non-CTICU). Adjusting for pre-ECMO characteristics and case mix, secondary outcomes were on-ECMO physiologic variables by ICU location stratified by support type.

resultsCTICU ECMO occurred in 65.1% and 55.1% (2018 and 2019) of total runs. A minority of total runs related to cardiac surgery procedures (CTICU: 21.7% [2018], 18% [2019]; non-CTICU: 11.2% [2018], 13% [2019]). After multivariate adjustment, non-CTICU ECMO for cardiac support associated with lower 4- and 24-h circuit flow (3.9 liters per minute [LPM] vs. 4.1 LPM, p < 0.0001; 4.1 LPM vs. 4.3 LPM, p < 0.0001); for respiratory support, lower on-ECMO mean fraction of inspired oxygen ([F

conclusionsECMO mostly remains in CTICUs though a minority is associated with cardiac surgery. Statistically significant but clinically minor differences in on-ECMO metrics were observed across ICU types.

Indexed as

Cardiopulmonary ResuscitationExtracorporeal Membrane OxygenationIntensive Care UnitsRegistriesRetrospective StudiesUnited Statescardiac critical carecardiac intensive care unitcardiothoracic intensive care unitCritical care deliveryECMOepidemiologyhealthcare deliverymultidisciplinary critical care

Identifiers

PMID35122290
PMCPMC9187583

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.