Evidence map›Paper›PMID 35122172›Full record

ArticleEJNMMI physics2022

Deep learning-assisted PET imaging achieves fast scan/low-dose examination.

Yan Xing, Wenli Qiao, Taisong Wang, Ying Wang, Chenwei Li, Yang Lv, Chen Xi, Shu Liao, Zheng Qian, Jinhua Zhao

Abstract read
In one paragraph

Article in EJNMMI physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Optimizing acquisition time and injected dose inBMC medical informatics and decision making · 2026
    Article
  5. Article
  6. An AI-Based Solution for Denoising Fast-Acquisition [Journal of imaging informatics in medicine · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. EJNMMI research · 2025
    Article
  12. EnhancingCancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. LowQuantitative imaging in medicine and surgery · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yan XingDepartment of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiaotong University, No. 100 Haining Road, Shanghai, 200080, People's Republic of China.
Wenli QiaoDepartment of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiaotong University, No. 100 Haining Road, Shanghai, 200080, People's Republic of China.
Taisong WangDepartment of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiaotong University, No. 100 Haining Road, Shanghai, 200080, People's Republic of China.
Ying WangUnited Imaging Healthcare, Shanghai, People's Republic of China.
Chenwei LiUnited Imaging Healthcare, Shanghai, People's Republic of China.
Yang LvUnited Imaging Healthcare, Shanghai, People's Republic of China.
Chen XiUnited Imaging Healthcare, Shanghai, People's Republic of China.
Shu LiaoShanghai United Imaging Intelligence Co. Ltd, Shanghai, People's Republic of China.
Zheng QianUnited Imaging Healthcare, Shanghai, People's Republic of China.
Jinhua ZhaoDepartment of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiaotong University, No. 100 Haining Road, Shanghai, 200080, People's Republic of China. zhaojinhua1963@126.com.ORCID http://orcid.org/0000-0002-8867-7985

Funding

science and technology commission of shanghai municipality 17411953200Shanghai Municipal Health Commission 201840076
6 · The paper itself

Abstract

purposeThis study aimed to investigate the impact of a deep learning (DL)-based denoising method on the image quality and lesion detectability of

methodsFifty-two oncological patients undergoing an

resultsThe DL method showed superior performance regarding image noise and inferior performance regarding lesion contrast in the qualitative assessment. More than 96.8% of the lesions were successfully identified in DL images. Excellent agreements on SUV in livers and lesions were found. The DL method significantly improved the liver SNR for count reduction down to 33.3% (p < 0.001). Lesion TBR was not significantly different between DL and reference images of the 75% dataset; furthermore, there was no significant difference either for lesions of > 10 mm or lesions in BMIs of > 25. For the 50% dataset, there was no significant difference between DL and reference images for TBR of lesion with > 15 mm or higher uptake than liver.

conclusionsThe developed DL method improved both liver SNR and lesion TBR indicating better image quality and lesion conspicuousness compared to GS method. Compared with the reference, it showed non-inferior image quality with reduced counts by 25-50% under various conditions.

Indexed as

Deep learningDenoising techniqueImage qualityPositron emission tomography and computed tomography (PET/CT)

Identifiers

PMID35122172
PMCPMC8816983

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.