Evidence map›Paper›PMID 35122160›Full record

ArticleArchives of osteoporosis2022

An update of the prevalence of osteoporosis, fracture risk factors, and medication use among community-dwelling older adults: results from the Canadian Longitudinal Study on Aging (CLSA).

Caitlin McArthur, Ahreum Lee, Hajar Abu Alrob, Jonathan D Adachi, Lora Giangregorio, Lauren E Griffith, Suzanne Morin, Lehana Thabane, George Ioannidis, Justin Lee and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Archives of osteoporosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Caitlin McArthurSchool of Physiotherapy, Dalhousie University, Forrest Building, P.O. Box 15000, Halifax, NS, B3H 4R2, Canada. caitlin.mcarthur@dal.ca.
Ahreum LeeGERAS Centre for Aging Research, Hamilton, Ontario, Canada.
Hajar Abu AlrobGERAS Centre for Aging Research, Hamilton, Ontario, Canada.
Jonathan D AdachiGERAS Centre for Aging Research, Hamilton, Ontario, Canada.
Lora GiangregorioDepartment of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada.
Lauren E GriffithHealth Research Methodology, McMaster University, Hamilton, Ontario, Canada.
Suzanne MorinDepartment of Medicine, McGill University, Montreal, Quebec, Canada.
Lehana ThabaneHealth Research Methodology, McMaster University, Hamilton, Ontario, Canada.
George IoannidisGERAS Centre for Aging Research, Hamilton, Ontario, Canada.
Justin LeeGERAS Centre for Aging Research, Hamilton, Ontario, Canada.
William D LeslieDepartments of Internal Medicine and Radiology, University of Manitoba, Winnipeg, Manitoba, Canada.
Alexandra PapaioannouGERAS Centre for Aging Research, Hamilton, Ontario, Canada.
McMaster University · CADalhousie University · CAMcGill University · CAUniversity of Manitoba · CAUniversity of Waterloo · CA

Funding

CIHR LSA 94473
6 · The paper itself

Abstract

The prevalence of self-reported and DXA-confirmed osteoporosis was 7.8% (males 2.2%; females 12.7%), and 3.6% (males 1.2%; females 5.9%), respectively. We found that most community-dwelling older adults at high fracture risk are not taking osteoporosis medication, particularly males. There is a major opportunity for improved primary fracture prevention in the community. PURPOSE: To provide an up-to-date prevalence estimate of osteoporosis, fracture risk factors, fracture risk, and the proportion of older Canadians at high fracture risk who are not taking an osteoporosis medication.

methodsWe included Canadian Longitudinal Study on Aging (CLSA) participants: a community-dwelling cohort aged 45 to 85 years who completed the baseline (2015) comprehensive interview and had dual-energy X-ray absorptiometry (DXA) scans (N = 30,097). We describe the age- and sex-stratified prevalence of (1) self-reported osteoporosis; (2) DXA-confirmed osteoporosis; (3) fracture risk factors and people who are at high risk (FRAX® major osteoporotic fracture probability ≥ 20%); and (4) people who are at high fracture risk not taking osteoporosis medications. Sampling weights, as defined by the CLSA, were applied.

resultsThe mean age of participants was 70.0 (SD 10.3). Overall, 7.8% had self-reported osteoporosis (males 2.2%; females 12.7%) while 3.6% had DXA-confirmed osteoporosis (males 1.2%; females 5.9%), and 2.8% were at high fracture risk (males 0.3%; females 5.1%). Of people who had osteoporosis and were at high risk, 77.3% were not taking an osteoporosis medication (males 92.3%; females 76.8%).

conclusionsOur study provides an up-to-date prevalence estimate of osteoporosis for community-dwelling older Canadians. We found that most community-dwelling older adults at high fracture risk are not taking an osteoporosis medication, particularly males. There is a major opportunity for improved primary fracture prevention in the community.

Indexed as

OsteoporosisOsteoporotic FracturesAbsorptiometry, PhotonAgedAged, 80 and overAgingBone DensityCanadaFemaleHumansIndependent LivingLongitudinal StudiesMaleMiddle AgedPrevalenceRisk AssessmentCLSAFractureFracture riskOsteoporosis

Identifiers

PMID35122160
PMCPMC8816745
OpenAlexW4210533366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.