Evidence map›Paper›PMID 35122149›Full record

ArticleSurgical endoscopy2022

Effects of surgical approach on short- and long-term outcomes in early-stage rectal cancer: a multicenter, propensity score-weighted cohort study.

William C Kethman, Katherine E Bingmer, Asya Ofshteyn, Ronald Charles, Sharon L Stein, David Dietz, Emily Steinhagen

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

William C KethmanDepartment of Surgery, Division of Colorectal Surgery, University Hospitals RISES: Research in Surgical Outcomes and Effectiveness, 11100 Euclid Ave, Cleveland, OH, 44106, USA.ORCID http://orcid.org/0000-0002-8210-844X
Katherine E BingmerDepartment of Surgery, Division of Colorectal Surgery, University Hospitals RISES: Research in Surgical Outcomes and Effectiveness, 11100 Euclid Ave, Cleveland, OH, 44106, USA.
Asya OfshteynDepartment of Surgery, Division of Colorectal Surgery, University Hospitals RISES: Research in Surgical Outcomes and Effectiveness, 11100 Euclid Ave, Cleveland, OH, 44106, USA.
Ronald CharlesDepartment of Surgery, Division of Colorectal Surgery, University Hospitals RISES: Research in Surgical Outcomes and Effectiveness, 11100 Euclid Ave, Cleveland, OH, 44106, USA.
Sharon L SteinDepartment of Surgery, Division of Colorectal Surgery, University Hospitals RISES: Research in Surgical Outcomes and Effectiveness, 11100 Euclid Ave, Cleveland, OH, 44106, USA.
David DietzDepartment of Surgery, Division of Colorectal Surgery, University Hospitals RISES: Research in Surgical Outcomes and Effectiveness, 11100 Euclid Ave, Cleveland, OH, 44106, USA.
Emily SteinhagenDepartment of Surgery, Division of Colorectal Surgery, University Hospitals RISES: Research in Surgical Outcomes and Effectiveness, 11100 Euclid Ave, Cleveland, OH, 44106, USA. Emily.Steinhagen@UHhospitals.org.
University Hospitals of Cleveland · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRandomized controlled trials have been unable to demonstrate noninferiority of minimally invasive surgery for rectal cancer. The aim of this study was to assess oncologic resection success, short- and long-term morbidity, and overall survival by operative approach in a homogenous early-stage rectal cancer cohort.

methodsThis is a multicenter, propensity score-weighted cohort study utilizing deidentified data from the National Cancer Database. Individuals who underwent a formal proctectomy for early-stage rectal cancer (T1-2, N0, M0) from 2010 to 2015 were included. The primary outcome was a composite variable indicating successful oncologic resection stratified by operative approach, defined as negative margins with at least 12 lymph nodes evaluated.

resultsAmong 3649 proctectomies for rectal adenocarcinoma, 1660 (45%) were approached open, 1461 (40%) laparoscopically, and 528 (15%) robotically. After propensity score weighting, compared to open approach, there were no differences in odds of successful oncologic resection (OR

conclusionFor individuals with early-stage rectal cancer treated with proctectomy, successful oncologic resection can be achieved irrespective of technical approach. Minimally invasive approaches provide short-term reduction in morbidity. Surgical approach must be tailored to each patient based on surgeon experience and judgement in collaboration with a multi-disciplinary team.

Indexed as

LaparoscopyRectal NeoplasmsRobotic Surgical ProceduresCohort StudiesHumansPropensity ScoreRetrospective StudiesTreatment OutcomeApproachLaparoscopicOpenRectal cancerRobotic

Identifiers

PMID35122149
OpenAlexW4210659798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.