Evidence map›Paper›PMID 35121633›Full record

Trial reportBMJ open respiratory research2022

Immediate smoking cessation support versus usual care in smokers attending a targeted lung health check: the QuLIT trial.

Sara C Buttery, Parris Williams, Rebecca Mweseli, Keir Elmslie James Philip, Ahmed Sadaka, Emily Jade Bartlett, Anand Devaraj, Samual Kemp, Jamie Addis, Jane Derbyshire and 4 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open respiratory research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05764343 (Investigation of the Effectiveness of Immediate Smoking Cessation Interventions During Routine Outpatient Service in Current Smoker Chronic Airway Disease Patients), which is not on this map. Cited by 22 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05764343 nacompletednot on this map

Investigation of the Effectiveness of Immediate Smoking Cessation Interventions During Routine Outpatient Service in Current Smoker Chronic Airway Disease Patients

TypeinterventionalSponsorRecep Tayyip Erdogan University Training and Research HospitalRan2022 to 2023Enrolled397ConditionsTobacco Cessation, Asthma COPD, Bronchiectasis AdultArmsImmediate smoking cessation support
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
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  6. Trial
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  13. Updates in Lung Cancer Screening: A Decade of Evidence.Seminars in respiratory and critical care medicine · 2025
    Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sara C Buttery *Imperial College London, London, UK.
Parris Williams *Imperial College London, London, UK parris.williams@imperial.ac.uk.
Rebecca MweseliRoyal Brompton and Harefield NHS Foundation Trust, London, UK.
Keir Elmslie James PhilipImperial College London, London, UK.ORCID 0000-0001-9614-3580
Ahmed SadakaRoyal Brompton and Harefield NHS Foundation Trust, London, UK.
Emily Jade BartlettRoyal Brompton and Harefield NHS Foundation Trust, London, UK.
Anand DevarajNational Heart and Lung Institute, Imperial College London, London, UK.
Samual KempRoyal Brompton and Harefield NHS Foundation Trust, London, UK.
Jamie AddisRoyal Brompton and Harefield NHS Foundation Trust, London, UK.
Jane DerbyshireRM Partners, London, UK.
Michelle ChenRM Partners, London, UK.
Katie MorrisRM Partners, London, UK.
Anthony LavertyImperial College London, London, UK.
Nicholas S HopkinsonImperial College London, London, UK.ORCID 0000-0003-3235-0454

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLung cancer screening programmes offer an opportunity to address tobacco dependence in current smokers. The effectiveness of different approaches to smoking cessation in this context has not yet been established. We investigated if immediate smoking cessation support, including pharmacotherapy, offered as part of a lung cancer screening programme, increases quit rates compared to usual care (Very Brief Advice to quit and signposting to smoking cessation services). MATERIALS AND

methodsWe conducted a single-blind randomised controlled trial of current smokers aged 55-75 years attending a Targeted Lung Health Check. On randomly allocated days smokers received either (1) immediate support from a trained smoking cessation counsellor with appropriate pharmacotherapy or (2) usual care. The primary outcome was self-reported quit rate at 3 months. We performed thematic analysis of participant interview responses.

resultsOf 412 people attending between January and March 2020, 115 (27.9%) were current smokers; 46% female, mean (SD) 62.4 (5.3) years. Follow-up data were available for 84 smokers. At 3 months, quit rates in the intervention group were higher 14/48 (29.2%) vs 4/36 (11%) (χ

conclusionThe provision of immediate smoking cessation support is associated with a substantial increase in quit rates at 3 months. Further research is needed to investigate longer-term outcomes and to refine future service delivery. TRIAL REGISTRATION NUMBER: ISRCTN12455871.

Indexed as

COVID-19Lung NeoplasmsSmoking CessationAgedCost-Benefit AnalysisEarly Detection of CancerFemaleHumansLungMaleMiddle AgedPandemicsSARS-CoV-2Single-Blind MethodSmokersimaging/CT MRI etclung cancertobacco and the lung

Identifiers

PMID35121633
PMCPMC8819808

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.