Evidence map›Paper›PMID 35120521›Full record

ArticleBiomedical engineering online2022

The oxygenation module: the missing link in using sleep apnea devices to treat COVID-19 pneumonia at home.

Dmitrijs Bliznuks, Svjatoslavs Kistkins, Jevgēnijs Teličko, Vadims Geža, Ģirts Zāģeris, Artis Svaža, Emil Syundyukov, Mārtiņš Purenkovs, Dana Zeme, Solveiga Jēkabsone and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical engineering online, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Dmitrijs BliznuksInstitute of Smart Computer Technologies, Riga Technical University, 2-335 Daugavgrivas street, Riga, 1658, Latvia. dmitrijs.bliznuks@rtu.lv.ORCID http://orcid.org/0000-0003-4252-9220
Svjatoslavs KistkinsDepartment of Internal Medicine, Paul Stradins Clinical University Hospital, 13 Pilsonu street, Riga, 1002, Latvia.
Jevgēnijs TeličkoUniversity of Latvia Institute of Numerical Modelling, 3 Jelgavas street, Riga, 1004, Latvia.
Vadims GežaUniversity of Latvia Institute of Numerical Modelling, 3 Jelgavas street, Riga, 1004, Latvia.
Ģirts ZāģerisUniversity of Latvia Institute of Numerical Modelling, 3 Jelgavas street, Riga, 1004, Latvia.
Artis SvažaPaul Stradins Clinical University Hospital, Research Institute, 13 Pilsonu street, Riga, 1002, Latvia.
Emil SyundyukovFaculty of Computing, University of Latvia, 19 Raina bulvaris, Riga, 1586, Latvia.
Mārtiņš PurenkovsDepartment of Internal Medicine, Paul Stradins Clinical University Hospital, 13 Pilsonu street, Riga, 1002, Latvia.
Dana ZemeDepartment of Internal Medicine, Paul Stradins Clinical University Hospital, 13 Pilsonu street, Riga, 1002, Latvia.
Solveiga JēkabsoneDepartment of Internal Medicine, Paul Stradins Clinical University Hospital, 13 Pilsonu street, Riga, 1002, Latvia.
Dace ŽentiņaDepartment of Internal Medicine, Paul Stradins Clinical University Hospital, 13 Pilsonu street, Riga, 1002, Latvia.
Valdis PīrāgsDepartment of Internal Medicine, Paul Stradins Clinical University Hospital, 13 Pilsonu street, Riga, 1002, Latvia.
Immanuels TaivansDepartment of Internal Medicine, Paul Stradins Clinical University Hospital, 13 Pilsonu street, Riga, 1002, Latvia.
Pauls Stradiņš Clinical University Hospital · LVUniversity of Latvia · LVRiga Technical University · LV

Funding

Latvijas Zinātnes Padome "VPP-COVID-2020/1-0025"
6 · The paper itself

Abstract

backgroundThe study aims at solving the problem with the limitations of the homecare CPAP equipment such as sleep apnea devices in the treatment of COVID-19 pneumonia. By adding an advanced, rapid-to-produce oxygenation module to existing CPAP devices we allow distributing healthcare at all levels, reducing the load on intensive care units, promoting treatment in the early stages at homecare. A significant part of the COVID-19 pneumonia patients requires not only an oxygen supply but also additional air pressure. Existing home care devices are able to create precise positive airway pressure, but cannot precisely measure supplied oxygen concentration. Either uses uncertified and potentially unsafe mechanisms.

resultsThe developed system allows using certified and widely available CPAP (constant positive airway pressure) devices to perform the critical function of delivering pressure and oxygen to airways. CPAP device is connected to the designed add-on module that can provide predefined oxygen concentration in a precise and stable manner. Clinical test results include data from 12 COVID-19 positive patients. The device has been compared against certified NIV (non-invasive) equipment under 6-20 hPa pressure and 30-70% FiO

conclusionThe clinical testing of the new device for oxygen supplementation of patients treated using simple CPAP devices looks promising and could be used for the treatment of COVID-19 pneumonia.

Indexed as

COVID-19Noninvasive VentilationSleep Apnea SyndromesContinuous Positive Airway PressureHumansLungSARS-CoV-2COVID-19Critical CareHomecareNon-invasive ventilationSleep apnea

Identifiers

PMID35120521
PMCPMC8814782
OpenAlexW4226124857

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.